Dr Henry De'Ath

Honorary Lecturer

I am general surgical registrar, with an interest in trauma and humanitarian surgery.  I completed a PhD at the C4TS and QMUL in 2013 investigating the secondary effects of trauma on the heart.

Research interests:

My main research interest lies in attempting to better understand TISCI (Trauma Induced Secondary Cardiac Injury).  In particular, to explore further the pathophysiological mechanisms that lead to the condition, and ultimately to establish management strategies designed to reduce the morbidity and mortality associated with TISCI. 

Contact

email: henryde-ath@doctors.org.uk

  • De'Ath HD, Wong S, Szentpali K et al. (2018). The Laparoscopic Management of Median Arcuate Ligament Syndrome and Its Long-Term Outcomes. J Laparoendosc Adv Surg Tech A .
    10.1089/lap.2018.0204
  • Wilson NM, Wall J, Naganathar V et al. (2017). Mechanisms Involved in Secondary Cardiac Dysfunction in Animal Models of Trauma and Hemorrhagic Shock. Shock 48, (4) 401-410.
    10.1097/SHK.0000000000000882
  • Shamali A, De'Ath HD, Jaber B et al. (2017). Elderly patients have similar short term outcomes and five-year survival compared to younger patients after pancreaticoduodenectomy. Int J Surg 45138-143.
    10.1016/j.ijsu.2017.07.106
  • De'Ath HD, Devoto L, Mehta C et al. (2017). Mentored Trainees have Similar Short-Term Outcomes to a Consultant Trainer Following Laparoscopic Colorectal Resection. World J Surg 41, (7) 1896-1902.
    10.1007/s00268-017-3925-7
  • Wilson NM, Wall J, Naganathar V et al. (2017). Mechanisms Involved in Secondary Cardiac Dysfunction in Animal Models of Trauma and Haemorrhagic Shock. Shock 48, (4) .
    10.1097/SHK.0000000000000882
  • De'Ath HD, Oakland K, Brohi K (2016). CT screened arterial calcification as a risk factor for mortality after trauma. Scand J Trauma Resusc Emerg Med 24, (1) 120-120.
    10.1186/s13049-016-0317-1
  • Chand M, De'Ath HD, Rasheed S et al. (2016). The influence of peri-operative factors for accelerated discharge following laparoscopic colorectal surgery when combined with an enhanced recovery after surgery (ERAS) pathway. Int J Surg 2559-63.
    10.1016/j.ijsu.2015.11.047
  • Chand M, De'Ath HD, Siddiqui M et al. (2015). Obese patients have similar short-term outcomes to non-obese in laparoscopic colorectal surgery. World J Gastrointest Surg 7, (10) 261-266.
    10.4240/wjgs.v7.i10.261
  • Naganathar S, De''Ath HD, Wall J et al. (2015). Admission biomarkers of trauma-induced secondary cardiac injury predict adverse cardiac events and are associated with plasma catecholamine levels. Journal of Trauma and Acute Care Surgery 79, (1) 71-77.
    10.1097/TA.0000000000000694
  • Khan S, Davenport R, Raza I et al. (2015). Damage control resuscitation using blood component therapy in standard doses has a limited effect on coagulopathy during trauma hemorrhage. Intensive Care Med 41, (2) 239-247.
    10.1007/s00134-014-3584-1
  • Chand M, De'Ath HD, Mehta C et al. (2015). Increased BMI does not Affect Short-Term Outcomes in Laparoscopic Colorectal Surgery. BRITISH JOURNAL OF SURGERY 10273-73.
  • De'Ath HD, Chand M, Hassan M et al. (2015). Length of Stay for Laparoscopic Anterior Resection is Shorter than for Right Hemicolectomy as Part of an Enhance Recovery Protocol. BRITISH JOURNAL OF SURGERY 10290-90.
  • De'Ath HD, Chand M, Mehta C et al. (2015). Patients Undergoing Laparoscopic Anterior Resections can be Discharged < 72 Hours with Low Readmission Rates when Combined with Enhanced Recovery. BRITISH JOURNAL OF SURGERY 102268-268.
  • Chand M, De'Ath HD, Hassan M et al. (2015). Quality of Resection Specimens in Laparoscopic Colorectal Surgery are Similar between Consultants and Trainees Undergoing a Mentored Training Program. BRITISH JOURNAL OF SURGERY 102122-122.
  • Chand M, De'Ath HD, Hassan M et al. (2015). Trainees Have Similar Operative Outcomes to Consultants when Mentored using a Modular Laparoscopic Training Programme in Colorectal Surgery. BRITISH JOURNAL OF SURGERY 102208-208.
  • Wilson NM, De'Ath HD, Manson J (2014). The role of inflammation in secondary cardiac dysfunction following trauma. Scand J Trauma Resusc Emerg Med 22, (1) 787-.
    10.1186/1757-7241-22-S1-P12
  • De'Ath HD, Sabharwal NK, Ormerod O et al. (2014). Patent foramen ovale and gut ischemia in potential intestinal transplant recipients. Transplantation 98, (6) e60-e61.
    10.1097/TP.0000000000000343
  • Khan S, Raza I, Davenport R et al. (2013). MAJOR HEMORRHAGE PROTOCOLS HAVE A LIMITED EFFECT ON TRAUMA-INDUCED COAGULOPATHY. SHOCK 4034-34.
  • Oakland K, De'Ath H, Brohi K (2013). The incidence of calcified atherosclerosis and association with in-hospital mortality in trauma. BRITISH JOURNAL OF SURGERY 10030-30.
  • De'Ath HD, Manson J, Davenport R et al. (2013). Trauma-induced secondary cardiac injury is associated with hyperacute elevations in inflammatory cytokines. Shock 39, (5) 415-420.
    10.1097/SHK.0b013e31828ded41
  • Raza I, Davenport R, Rourke C et al. (2013). The incidence and magnitude of fibrinolytic activation in trauma patients. J Thromb Haemost 11, (2) 307-314.
    10.1111/jth.12078
  • Cole E, Davenport R, De'Ath H et al. (2013). Coagulation system changes associated with susceptibility to infection in trauma patients. J Trauma Acute Care Surg 74, (1) 51-57.
    10.1097/TA.0b013e3182788b0f
  • De'Ath HDI, Vulliamy PED, Davies C et al. (2012). A large ventricular septal defect complicating resuscitation after blunt trauma. J Emerg Trauma Shock 5, (4) 350-352.
    10.4103/0974-2700.102409
  • Perkins ZB, De'Ath HD, Aylwin C et al. (2012). Epidemiology and outcome of vascular trauma at a British Major Trauma Centre. Eur J Vasc Endovasc Surg 44, (2) 203-209.
    10.1016/j.ejvs.2012.05.013
  • De'Ath HD, Rourke C, Davenport R et al. (2012). Clinical and biomarker profile of trauma-induced secondary cardiac injury. British Journal of Surgery 99, (6) 789-797.
    10.1002/bjs.8728
  • De'Ath HD, Rourke C, Davenport R et al. (2012). Clinical and biomarker profile of trauma-induced secondary cardiac injury. Br J Surg 99, (6) 789-797.
    10.1002/bjs.8728
  • Perkins ZB, De'Ath HD, Sharp G et al. (2012). Factors affecting outcome after traumatic limb amputation. BRITISH JOURNAL OF SURGERY 9975-86.
    10.1002/bjs.7766
  • Oakland K, De'Ath H, Brohi K (2012). Mesenteric Vessel Calcification Predicts Mortality in Older Trauma Patients. BRITISH JOURNAL OF SURGERY 9939-39.
  • Davenport R, Manson J, De'Ath H et al. (2011). Functional definition and characterization of acute traumatic coagulopathy. Crit Care Med 39, (12) 2652-2658.
    10.1097/CCM.0b013e3182281af5
  • De' Ath HD, Rourke C, Manson J et al. (2011). Trauma induced secondary cardiac injury. EUROPEAN HEART JOURNAL 32726-726.
  • Khan S, Brohi K, Davenport R et al. (2011). A major haemorrhage protocol improves blood product administration and wastage compared to traditional massive transfusion protocols. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 9691-692.
  • Davenport R, Rourke C, Manson J et al. (2011). Activated protein C is a principle mediator of acute traumatic coagulopathy. J THROMB HAEMOST 951-52.
  • Raza I, Davenport R, Brohi K et al. (2011). Dilutional coagulopathy following blood transfusion in trauma. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 9692-693.
  • Raza I, Davenport R, Rourke C et al. (2011). Occult activation of fibrinolysis in trauma. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 9848-848.
  • Spoors CM, Davenport R, De'Ath H et al. (2011). Platelet function in trauma measured by multiple electrode aggregometry. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 9799-799.
  • Manson J, Davenport R, Coates A et al. (2011). TRAUMATIC TISSUE DAMAGE: THE SEARCH FOR TRAUMA ALARMINS. INFLAMMATION RESEARCH 60160-160.
  • Perkins Z, De'Ath H, Walker R et al. (2011). Vascular trauma: a UK trauma centre experience. BRITISH JOURNAL OF SURGERY 9852-52.
  • De'Ath HDI, Rourke C, Davenport R et al. (2011). Cardiac dysfunction after trauma: A real and present danger. BRITISH JOURNAL OF SURGERY 987-8.
  • Davenport R, Manson J, De'Ath H et al. (2011). Point of care diagnostics for the rapid identification of acute traumatic coagulopathy and prediction of massive trauma haemorrhage. BRITISH JOURNAL OF SURGERY 987-7.
  • Spoors C, Rourke C, Manson J et al. (2011). Rotem indices of platelet function in acute traumatic coagulopathy. BRITISH JOURNAL OF SURGERY 988-8.
  • Manson J, Davenport R, Coates A et al. (2011). Trauma: Characterising the cytokine response to tissue damage. BRITISH JOURNAL OF SURGERY 9822-22.
  • Manson J, Davenport R, Coates A et al. (2011). DEMONSTRATING THE HUMAN CYTOKINE RESPONSE TO TISSUE DAMAGE AFTER TRAUMATIC INJURY. SHOCK 3623-23.
  • Davenport R, Curry N, Manson J et al. (2011). Hemostatic effects of fresh frozen plasma may be maximal at red cell ratios of 1:2. J Trauma 70, (1) 90-95.
    10.1097/TA.0b013e318202e486
  • Chana MS, Manson J, Davenport R et al. (2011). TIME COURSE OF LACTATE CLEARANCE IN TRAUMA AND ITS RELEVANCE TO OUTCOMES. SHOCK 3610-11.
  • De'Ath H, Manson J, Rourke C et al. (2011). TRAUMA INDUCED SECONDARY CARDIAC INJURY IS ASSOCIATED WITH ACUTE INFLAMMATION. SHOCK 3612-12.
  • De' Ath HD, Rourke C, Manson J et al. (2011). Trauma induced secondary cardiac injury. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 183726-726.
  • De'Ath HDI, Lovegrove RE, Javid M et al. (2010). An assessment of between-recti distance and divarication in patients with and without abdominal aortic aneurysm. Ann R Coll Surg Engl 92, (7) 591-594.
    10.1308/003588410X12771863937089
  • De'Ath HDI, Galland RB (2010). Iatrogenic and non-iatrogenic vascular trauma in a district general hospital: a 21-year review. World J Surg 34, (10) 2363-2367.
    10.1007/s00268-010-0647-5
  • Collins JPW, Roberts DMC, Evans CFM et al. (2009). Public perception of Clostridium difficile. J Hosp Infect 72, (1) 80-81.
    10.1016/j.jhin.2009.02.007
  • Kambal AA, De'Ath HD, Albon H et al. (2008). Endovenous laser ablation for persistent and recurrent venous ulcers after varicose vein surgery. Phlebology 23, (4) 193-195.
    10.1258/phleb.2008.006044
  • De'Ath HDI (2008). Perforation of a sigmoid diverticulum presenting with a pneumoscrotum and surgical emphysema. BMJ Case Rep 2008bcr0820080834-.
    10.1136/bcr.08.2008.0834
  • De'Ath H (2008). The need for rigid cystoscopy and resection of tumour (TURBT) - Author's response. ANN ROY COLL SURG 90, (1) 89-89.
    10.1308/003588408X242213
  • De'Ath HDI, Kayes O (2007). The use of cough to sample detrusor muscle during flexible cystoscopic biopsy. ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND 89, (5) 537-537.
    10.1308/rcsann.2007.89.5.537c
  • De'Ath HDI, Watson A, Hussain T (2006). Mid-term results of endovascular repair of abdominal aortic aneurysm (Br J Surg 2005; 92: 925-927); Cost-effectiveness of endovascular abdominal aortic aneurysm repair (Br J Surg 2005; 92: 960-967). Br J Surg 93, (2) 250-.
    10.1002/bjs.5307
  • MEIER U (). Early changes within the lymphocyte population are associated with the development of multiple organ dysfunction syndrome in trauma patients. Critical Care .
    10.1186/s13054-016-1341-2

 

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