Dr Elaine Cole PhD, MSc, BSc, RN

Director of Research and Innovation, Pan London Major Trauma System

I have worked for a number of years in the field of trauma, including ED clinical trauma care, developing and teaching trauma education and more recently, research.

Research Interests

I am currently working as the Director of Research and Innovation for the pan- London Major Trauma System. Within this role I work with clinical, academic and managerial staff within the four major trauma networks and pre hospital providers in the London Major Trauma System to support the development of innovation, collaborative research and education across the system as a whole.

Trauma systems are relatively new to the UK and I co-led the evaluation of the London Trauma System (ELOTS) which reported improvements in care quality and patient outcomes since the system was introduced in 2010. From February 2018, this evaluation is being repeated in collaboration with all four trauma networks with a focus on paediatric trauma across the system via the PELOTS study

My current main research focusses on the risks and phenotypes of contemporary multiple organ dysfunction (MODS) after major trauma. In 2016, I led a national point prevalence study called ORDIT (Organ Dysfunction in Trauma), which involved all Major Trauma Centres in England, Wales and Scotland. The findings of this study are in write-up, where we have described three distinct patterns of recovery after MODS and the associated risks of developing differing phenotypes of dysfunction from a national perspective.

I am the Chief Investigator for the pan-London Dunhill Medical Trust funded study called MODET. The research is being carried out by teams at the four London Major Trauma Centres and is investigating the characteristics, predictors and outcomes of MODS in severely injured older patients. This important research will help us better understand needs of and plan the for an increasing elderly major trauma population.

Teaching

I am a lecturer, module leader and dissertation supervisor for the MSc in Trauma Sciences. This international online MSc provides its multi-professional students with the opportunity to learn together about all aspects of trauma care in a virtual, interactive format, with access to many of the global leaders in clinical trauma management.

Key publications:

Shepherd JM, Cole E, Brohi K. Contemporary patterns of multiple organ dysfunction in trauma.  Shock, 2017 Apr;47(4):429-435.

Manson J, Cole E, De'Ath HD, Vulliamy P, Meier U, Pennington D, Brohi K.Early changes within the lymphocyte population are associated with the development of multiple organ dysfunction syndrome in trauma patients.  Crit Care. 2016 Jun 7;20(1):176. 

Cole E, Davenport R, Willett K, Brohi K. Tranexamic acid use in severely injured civilian patients and the effects on outcomes. Ann Surg. 2015 Feb; 261(2):390-4.

Cole E, Davenport R, Willett K, Brohi K. The burden of infection in severely injured trauma patients and the relationship with admission shock severity. J Trauma Acute Care Surg. 2014 Mar; 76(3):730-5.

Cole E, Davenport R, De'Ath H, Manson J, Brockamp T, Brohi K. Coagulation system changes associated with susceptibility to infection in trauma patients. J Trauma Acute Care Surg. 2013 Jan; 74(1):51-7; discussion 57-8.

Contact

email: e.cole@qmul.ac.uk 
Tel: +44 (0) 203 594 0731

  • Wohlgemut JM, Davies J, Aylwin C et al. (2018). Functional inclusivity of trauma networks: a pilot study of the North West London Trauma Network. Journal of Surgical Research 231201-209.
    10.1016/j.jss.2018.05.045
  • Adams RDF, Cole E, Brundage SI et al. (2018). Beliefs and expectations of rural hospital practitioners towards a developing trauma system: A qualitative case study. Injury 49, (6) 1070-1078.
    10.1016/j.injury.2018.03.025
  • Shepherd JM, Cole E, Brohi K (2016). Contemporary patterns of multiple organ dysfunction in trauma. Shock .
    10.1097/SHK.0000000000000779
  • Whiting D, Cole E (2016). Developing a trauma care syllabus for intensive care nurses in the United Kingdom: A Delphi study. Intensive Crit Care Nurs 3649-57.
    10.1016/j.iccn.2016.03.006
  • Cole E, Lecky F, West A et al. (2016). The Impact of a Pan-regional Inclusive Trauma System on Quality of Care. Ann Surg 264, (1) 188-194.
    10.1097/SLA.0000000000001393
  • Heim C, Cole E, West A et al. (2016). Survival prediction algorithms miss significant opportunities for improvement if used for case selection in trauma quality improvement programs. Injury .
    10.1016/j.injury.2016.05.042
  • Cole E (2015). How regional trauma systems improve outcomes. Emerg Nurse 23, (6) 24-29.
    10.7748/en.23.6.24.s23
  • Shepherd JM, Cole E, Brohi K (2015). PATTERNS OF MULTI-ORGAN DYSFUNCTION IN SEVERELY INJURED PATIENTS WITH HAEMORRHAGE. SHOCK 4421-21.
  • Shepherd JM, Cole E, Brohi K (2015). T-5: PATTERNS OF MULTI-ORGAN DYSFUNCTION IN SEVERELY INJURED PATIENTS WITH HAEMORRHAGE. Shock 44 Suppl 221-.
    10.1097/01.shk.0000472070.23771.ef
  • Zinchenko R, Cole E, Glasgow S et al. (2015). Mild, moderate or severe lung injury after trauma: What are the early predictors?. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 23, (2) .
    10.1186/1757-7241-23-S2-A8
  • Perkins ZB, Yet B, Glasgow S et al. (2015). Meta-analysis of prognostic factors for amputation following surgical repair of lower extremity vascular trauma. Br J Surg 102, (5) 436-450.
    10.1002/bjs.9689
  • Cole E, Davenport R, Willett K et al. (2015). Tranexamic acid use in severely injured civilian patients and the effects on outcomes: a prospective cohort study. Ann Surg 261, (2) 390-394.
    10.1097/SLA.0000000000000717
  • Cole E, Davenport R (2015). Early tranexamic acid use in trauma haemorrhage: Why do we give it and which patients benefit most?. International Emergency Nursing 23, (1) 38-41.
    10.1016/j.ienj.2014.03.004
  • Cole E, Davenport R (2015). Early tranexamic acid use in trauma haemorrhage: why do we give it and which patients benefit most?. Int Emerg Nurs 23, (1) 38-41.
    10.1016/j.ienj.2014.03.004
  • Perkins ZB, Yet B, Glasgow S et al. (2015). Meta-analysis of prognostic factors for amputation following surgical repair of lower extremity vascular trauma. British Journal of Surgery 102, (5) 436-450.
    10.1002/bjs.9689
  • Cole E, Davenport R, Willett K et al. (2014). The burden of infection in severely injured trauma patients and the relationship with admission shock severity. Journal of Trauma and Acute Care Surgery 76, (3) 730-735.
    10.1097/TA.0b013e31829fdbd7
  • Cole E, Davenport R, Willett K et al. (2014). The burden of infection in severely injured trauma patients and the relationship with admission shock severity. J Trauma Acute Care Surg 76, (3) 730-735.
    10.1097/TA.0b013e31829fdbd7
  • Hoffman K, Cole E, Playford ED et al. (2014). Health outcome after major trauma: what are we measuring?. PLoS One 9, (7) e103082-.
    10.1371/journal.pone.0103082
  • Crossan L, Cole E (2014). NURSING CHALLENGES WITH A SEVERELY INJURED PATIENT IN CRITICAL CARE: THE IMPORTANCE OF HYPOTHERMIA MITIGATION Reply. NURSING IN CRITICAL CARE 19, (1) 51-51.
    10.1111/nicc.12072
  • Khan S, Raza I, Davenport R et al. (2013). MAJOR HEMORRHAGE PROTOCOLS HAVE A LIMITED EFFECT ON TRAUMA-INDUCED COAGULOPATHY. SHOCK 4034-34.
  • Crossan L, Cole E (2013). Nursing challenges with a severely injured patient in critical care. NURSING IN CRITICAL CARE 18, (5) 236-244.
    10.1111/nicc.12019
  • Willink M, Khan S, Cole E et al. (2013). OUTCOMES FOLLOWING TRAUMA HEMORRHAGE. SHOCK 4028-29.
  • Cole E, Davenport R, Glasgow S et al. (2013). TRANEXAMIC ACID USE IN SHOCKED SEVERELY INJURED PATIENTS AND THE EFFECTS ON OUTCOMES. SHOCK 4021-21.
  • Cole EM, West A, Davenport R et al. (2013). Can residents be effective trauma team leaders in a major trauma centre?. Injury 44, (1) 18-22.
    10.1016/j.injury.2011.09.020
  • Cole E, Davenport R, De'Ath H et al. (2013). Coagulation system changes associated with susceptibility to infection in trauma patients. J Trauma Acute Care Surg 74, (1) 51-57.
    10.1097/TA.0b013e3182788b0f
  • Manson J, Cooper S, West A et al. (2013). Major trauma and urban cyclists: physiological status and injury profile. Emerg Med J 30, (1) 32-37.
    10.1136/emermed-2011-200966
  • Hoffman K, West A, Nott P et al. (2013). Measuring acute rehabilitation needs in trauma: Preliminary evaluation of the Rehabilitation Complexity Scale. Injury 44, (1) 104-109.
    10.1016/j.injury.2011.11.001
  • Hoffman K, West A, Nott P et al. (2013). Measuring acute rehabilitation needs in trauma: preliminary evaluation of the Rehabilitation Complexity Scale. Injury 44, (1) 104-109.
    10.1016/j.injury.2011.11.001
  • Brohi K, Cole E, Hoffman K (2011). Improving outcomes in the early phases after major trauma. Curr Opin Crit Care 17, (5) 515-519.
    10.1097/MCC.0b013e32834a9353
  • Cole E, Crichton N (2006). The culture of a trauma team in relation to human factors. J Clin Nurs 15, (10) 1257-1266.
    10.1111/j.1365-2702.2006.01566.x
  • Bradbury G, Cole E, Cranston C et al. (2005). Dealing with disaster. Nurs Manag (Harrow) 12, (5) 13-17.
    10.7748/nm.12.5.13.s11
  • MEIER U (). Early changes within the lymphocyte population are associated with the development of multiple organ dysfunction syndrome in trauma patients. Critical Care .
    10.1186/s13054-016-1341-2
 


BtLC Cycling and Trauma Seminar chaired by Jon Snow

I presented ‘How are we addressing long-term outcomes and the need for rehabilitation?’ at the BtLC Cycling and Trauma Seminar 2014. Patient rehabilitation is a complicated and layered process. Due to improved clinical intervention more trauma patients are surviving multiple injuries, with a large percentage requiring long-term care. Only two thirds of patients return to full time work 4-6 months after injury. This impaired quality of life not only seriously affects their physical, psychological and social wellbeing, but can shatter the lives of everyone around them, and also has wider economic implications. Click here to see a video recording of my  presentation.

 

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