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September 22, 2015
C4TS will be sharing many of our latest research findings at the XV1 European Shock Society (ESS) Congress in Cologne on 25-27 Sept 2015. This Congress will be held in conjunction with the 14th International Conference on Complexity in Acute Illness (ICCAI). The ESS Congress invites outstanding epidemiologists, clinicians and basic scientists while ICCAI gathers highly recognized mathematicians, engineers, system biologists, clinicians, modelers and partners from the industry to share the most recent advances in filling translational gaps between the triangle of bench, silicon and bedside for overall improved patient care and outcome. This year's theme “Improvement in care by translational exchange” echos C4TS's core mission, and we are looking forward to engaging on this topic with more than 400 fellow participants from around the globe. The full program for the Congress can be found here.
Abstracts of the papers and posters that C4TS researchers are presenting are listed below.
T-5: PATTERNS OF MULTI-ORGAN DYSFUNCTION IN SEVERELY INJURED PATIENTS WITH HAEMORRHAGE. Shepherd JM, Cole E, Brohi K.
T-6: HEART FATTY ACID BINDING PROTEIN (H-FABP) IS A BIOMARKER OF TRAUMA-INDUCED SECONDARY CARDIAC INJURY IN A PRE-CLINICAL MODEL OF TRAUMA-HAEMORRHAGE. Wall JM, Tremoleda JL, Thiemermann C, Brohi K.
T-12: VENOUS THROMBOEMBOLIC EVENTS AFTER TRAUMATIC INJURY ARE ASSOCIATED WITH EARLY CHANGES TO THE FIBRINOLYTIC SYSTEM. Jones TF, Gillespie S, Gall LS, Davenport RA, Brohi K.
T-14: IN VIVO IMAGING OF NEUROINFLAMMATION IN NEUROTRAUMA PRECLINICAL MODELS: POTENTIAL FOR CLINICAL TRANSLATION. Tremoleda JL, Thau-Zuchman O, Davies M, Foster J, Khan I, Trigg W, Sosabowski J, Mather SJ, Michael-Titus A.
HEM-3: TRAUMA ORGAN PROTECTION WITH ARTESUNATE (TOP-ART): PRECLINICAL EFFICACY OF AN ANTIMALARIAL DRUG WITH EXCELLENT SAFETY PROFILE AND PLANNED PHASE II RCT. Sordi R, Nandra KK, Chiazza F, Patel NS, Brohi K, Collino M, Thiemermann C.
HEM-4: THROMBIN GENERATION POTENTIAL DECLINES DURING TRAUMA HAEMORRHAGE DESPITE HAEMOSTATIC RESUSCITATION. Frith D, Wall J, Baptista M, Brohi K.
HEM-11: TRANEXAMIC ACID IS ASSOCIATED WITH ENHANCED CLOT STRENGTH, REDUCED FIBRINOLYSIS AND REDUCED ACUTE TRAUMATIC COAGULOPATHY IN BLEEDING TRAUMA PATIENTS. Gall L, Davenport R, Brohi K.
HEM-15: DEVELOPING TRANSFUSION BASED STRATEGIES FOR OPTIMISING OUTCOMES FOLLOWING MASS CASUALTY EVENTS USING A DISCRETE EVENT SIMULATION MODELLING APPROACH. Glasgow S, Vasilakis C, Perkins Z, Tai N, Brohi K.
SEP-9: THE CARDIAC DYSFUNCTION CAUSED BY SEPSIS IN ANIMALS WITH CHRONIC KIDNEY DISEASE IS ATTENUATED BY INHIBITING IκB KINASE. Chen J, Kieswich J, Chiazza F, Gobbetti T, Patel NS, Perretti M, Collino M, Yaqoob MM, Thiemermann C.
SEP-13: ENHANCED SPHINGOSINE-1-PHOSPHATE LEVELS ATTENUATE CARDIAC DYSFUNCTION IN EXPERIMENTAL SEPTIC CARDIOMYOPATHY. Coldewey SM, Benetti E, Collino M, Bauer M, Huwiler A, Thiemermann C.
INF/IR-11: THE LATE INHIBITION OF INHIBITOR OF IKB KINASE ATTENUATES ACUTE KIDNEY INJURY AND THE SUBSEQUENT DEVELOPMENT OF FIBROSIS IN A RAT MODEL OF ISCHAEMIA REPERFUSION INJURY. Johnson F, Patel N, Collino M, Bennetti E, Thiemermann C.
INF/IR-13: SEVERE LYMPHOPENIA IN EMERGENCY SURGICAL PATIENTS IS ASSOCIATED WITH ILLNESS SEVERITY AND MORTALITY. Vulliamy PE, Perkins ZB, Brohi K, Manson J.
