Dr Elaine Cole

Research
I am the Director of Research and Innovation for the London Major Trauma System. Within this role I work with clinical and academic staff within the four major trauma networks and pre hospital providers in the London Major Trauma System to support the development of innovation, collaborative research and education across the system. I co-led the evaluation of the London Trauma System (ELOTS) which reported improvements in care quality and patient outcomes since the system was introduced in 2010.
My main research interests are investigating the predictors and phenotypes of contemporary multiple organ dysfunction (MODS) after major trauma, and the impact of severe injury on older people. In 2016, I led a national point prevalence study called ORDIT (Organ Dysfunction in Trauma), which involved all Major Trauma Centres in England, Wales and Scotland.
I was the Chief Investigator for the pan-London Dunhill Medical Trust funded study called MODET. The study was carried out by research teams at the four London Major Trauma Centres investigating the characteristics, predictors and outcomes of MODS in severely injured older patients. This important research will help us better understand needs of and plan acute care for an increasing older major trauma population.
Teaching/Academic
I am a Senior lecturer in Trauma Sciences within the Blizard Institute. I co-lead the MSc in Trauma Sciences, the research methods module and dissertation year. This international online MSc provides its multi-professional students with the opportunity to enhance their knowledge about all aspects of trauma care in a virtual, interactive format, with access to many of the global leaders in clinical trauma management. Within my role I supervise MSc and PhD students, supporting their research projects and publications.
I also co-lead the Trauma Sciences and Care of the Injured Patient Programme (TSCIPP). This undergraduate SSC provides students with the unique opportunity to gain professional experience in trauma care and clinical research through a structured four-year programme with embedded placements within multidisciplinary teams at Barts Health and the Centre for Trauma Sciences.
Contact
email: e.cole@qmul.ac.uk
- Almuwallad A, Cole E, Rossetto A et al. (2023). Nationwide analysis of pre-hospital tranexamic acid for trauma demonstrates systematic bias in adherence to treatment guidelines: a retrospective cohort study. Int J Surg .
10.1097/JS9.0000000000000712 - Clough R, Platt E, Cole E et al. (2023). WTP4.14 Major Trauma Amongst E-scooter and Bicycle Users: A Nationwide Cohort Study. British Journal of Surgery 110, (Supplement_6) znad241.193-.
10.1093/bjs/znad241.193 - Battle C, Cole E, Whelan R et al. (2023). Scoping review of the literature to ascertain how the STUMBL Score clinical prediction model is used to manage patients with blunt chest wall trauma in emergency care. Injury 54, (7) 110796-.
10.1016/j.injury.2023.05.027 - Rehman U, Cole E, Whiteman E et al. (). Soft tissue reconstruction of combat-related injuries affecting the lower limb: is a time target realistic? A systematic review and meta-analysis. European Journal of Plastic Surgery 1-12.
10.1007/s00238-023-02095-9 - Clough RA, Platt E, Cole E et al. (2023). Major trauma among E-Scooter and bicycle users: a nationwide cohort study. Inj Prev 29, (2) 121-125.
10.1136/ip-2022-044722 - Jarman H, Crouch R, Friend S et al. (2023). Establishing the research priorities for major trauma in the United Kingdom: A Delphi study of nurses and allied health professionals. Int Emerg Nurs 67101265-.
10.1016/j.ienj.2023.101265 - Halter M, Jarman H, Moss P et al. (2023). Configurations and outcomes of acute hospital care for frail and older patients with moderate to major trauma: a systematic review. BMJ Open 13, (2) e066329-.
10.1136/bmjopen-2022-066329 - Agius C, Cole E, Mifsud MG et al. (2022). The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis. J Orthop Trauma 36, (12) e442-e448.
10.1097/BOT.0000000000002440 - Jarman H, Crouch R, Halter M et al. (2022). Provision of acute care pathways for older major trauma patients in the UK. BMC Geriatr 22, (1) 915-.
10.1186/s12877-022-03615-1 - Lucena-Amaro S, Cole E, Zolfaghari P (2022). Long term outcomes following rib fracture fixation in patients with major chest trauma. Injury 53, (9) 2947-2952.
10.1016/j.injury.2022.04.020 - Cole E, Curry N, Davenport R (2022). Sex discrimination after injury: is inequity in tranexamic acid administration just the tip of the iceberg?. British Journal of Anaesthesia 129, (2) 144-147.
10.1016/j.bja.2022.05.015 - Ebeid A, Cole E, Stallwood-Hall C (2022). The efficacy of weight-based enoxaparin dosing for venous thromboembolism prophylaxis in trauma patients: A systematic review and meta-analysis. Journal of Trauma and Acute Care Surgery 93, (2) E71-E79.
10.1097/TA.0000000000003707 - Cole E (). The national major trauma system within the United Kingdom: inclusive regionalized networks of care. Emergency and Critical Care Medicine 2, (2) 76-79.
10.1097/ec9.0000000000000040 - Jarman H, Crouch R, Baxter M et al. (2022). 1080 NURSES’ PREFERENCE FOR TOOLS TO IDENTIFY FRAILTY IN MAJOR TRAUMA PATIENTS: FINDINGS FROM THE FRAIL-T IN MAJOR TRAUMA STUDY. Age and Ageing 51, (Supplement_2) .
10.1093/ageing/afac125.010 - Cole E, Aylwin C, Christie R et al. (2022). Multiple Organ Dysfunction in Older Major Trauma Critical Care Patients: A Multicenter Prospective Observational Study. Ann Surg Open 3, (2) e174-.
10.1097/AS9.0000000000000174 - Eichinger M, Schreiber MA, Cole E et al. (). Injuries associated with hypotension after trauma: Is it always haemorrhage?. Trauma (London, England) 146040862210994-.
10.1177/14604086221099422 - Jarman H, Cole E, Crouch R et al. (2022). 734 ACUTE CARE PATHWAYS FOR OLDER MAJOR TRAUMA PATIENTS: A SURVEY OF UK PRACTICE. Age and Ageing 51, (Supplement_1) .
10.1093/ageing/afac035.734 - Jarman H, Crouch R, Baxter M et al. (2022). 803 QUALITY OF LIFE IN OLDER TRAUMA PATIENTS AFTER INJURY: FINDINGS FROM THE FRAILTY IN MAJOR TRAUMA STUDY (FRAIL-T). Age and Ageing 51, (Supplement_1) .
10.1093/ageing/afac037.803 - Jarman H, Crouch R, Baxter M et al. (2021). Feasibility and accuracy of ED frailty identification in older trauma patients: a prospective multi-centre study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 29, (1) .
10.1186/s13049-021-00868-4 - Green L (2021). Refining mass casualty plans with simulation based iterative learning. BJA: British Journal of Anaesthesia .
10.1016/j.bja.2021.10.004 - Elbourne C, Cole E, Marsh S et al. (2021). At risk child: A contemporary analysis of injured children in London and the South East of England: A prospective, multicentre cohort study. BMJ Paediatrics Open 5, (1) .
10.1136/bmjpo-2021-001114 - Boulton AJ, Peel D, Rahman U et al. (2021). Evaluation of elderly specific pre-hospital trauma triage criteria: a systematic review. Scand J Trauma Resusc Emerg Med 29, (1) 127-.
10.1186/s13049-021-00940-z - Anagnostou E, Cole E (2021). Targeted prevention of road traffic deaths in Greece: a multifactorial 5-year census-based study. Eur J Trauma Emerg Surg 47, (4) 1137-1152.
10.1007/s00068-019-01290-3 - Agius C, Cole E (2021). Acute compartment syndrome (ACS) - a case of delayed diagnosis. Int J Orthop Trauma Nurs 42100845-.
10.1016/j.ijotn.2021.100845 - Almuwallad A, Cole E, Ross J et al. (2021). The impact of prehospital TXA on mortality among bleeding trauma patients: A systematic review and meta-analysis. Journal of Trauma and Acute Care Surgery 90, (5) 901-907.
10.1097/TA.0000000000003120 - Sabin EJ, Cole E (2022). Major trauma centre Lead Clinicians: An evaluation of current practice in major trauma centres in England. Trauma (London, England) 24, (1) 61-67.
10.1177/1460408620974982 - Jarman H, Crouch R, Baxter M et al. (2020). 251 The frailty in major trauma study (FRAIL-T): feasibility of nurse lead frailty assessment in elderly trauma and the impact on outcomes. Emergency Medicine Journal 37, (12) 840-840.
10.1136/emj-2020-rcemabstracts.30 - Morgan O, Yarham E, Hudson A et al. (2021). Do pre-hospital physicians improve mortality in major trauma patients? A systematic review. Trauma (London, England) 23, (1) 3-12.
10.1177/1460408620953056 - Braasch MC, Turco LM, Cole EM et al. (2020). The evolution of initial-hemostatic resuscitation and the void of posthemostatic resuscitation. Journal of Trauma and Acute Care Surgery 89, (3) 597-601.
10.1097/TA.0000000000002576 - Braasch MC, Turco LM, Cole EM et al. (2020). The evolution of initial-hemostatic resuscitation and the void of posthemostatic resuscitation. J Trauma Acute Care Surg 89, (3) 597-601.
10.1097/TA.0000000000002576 - Jarman H, Crouch R, Baxter M et al. (2020). Frailty in major trauma study (FRAIL-T): A study protocol to determine the feasibility of nurse-led frailty assessment in elderly trauma and the impact on outcome in patients with major trauma. BMJ Open 10, (8) .
10.1136/bmjopen-2020-038082 - Luckey-Smith KN, High KR, Cole EM (2020). Effectiveness of Surgical Airway Training Lab and Assessment of Skill and Knowledge Fade in Surgical Airway Establishment Among Prehospital Providers. Air Medical Journal 39, (4) 244-.
10.1016/j.amj.2020.05.003 - Luckey-Smith K, High K, Cole E (2020). Effectiveness of Surgical Airway Training Laboratory and Assessment of Skill and Knowledge Fade in Surgical Airway Establishment Among Prehospital Providers. Air Med J 39, (5) 369-373.
10.1016/j.amj.2020.05.019 - Cubitt M, Downie E, Shakerian R et al. (2020). Timing and methods of frailty assessments in geriatric trauma patients: A Systematic Review. AUSTRALASIAN JOURNAL ON AGEING 3936-36.
- COLE ELAINE, Gillespie S, Vulliamy P et al. (). Multiple organ dysfunction after trauma. British Journal of Surgery .
10.1002/bjs.11361 - Go KT, Cheng JY, Seah X et al. (2019). The Changing Epidemiology of Serious Trauma in the Elderly Population: An Increasing Concern of a Tertiary Hospital in Singapore. Ann Acad Med Singap 48, (11) 354-362.
10.47102/annals-acadmedsg.v48n11p354 - Cubitt M, Downie E, Shakerian R et al. (2019). Timing and methods of frailty assessments in geriatric trauma patients: A systematic review. Injury 50, (11) 1795-1808.
10.1016/j.injury.2019.07.026 - Cole E, Weaver A, Gall L et al. (2019). A Decade of Damage Control Resuscitation: New Transfusion Practice, New Survivors, New Directions. Ann Surg .
10.1097/SLA.0000000000003657 - Schyma BM, Cole E, Wren SM et al. (2019). Delivering trauma mastery with an international trauma masters. Injury 50, (4) 877-882.
10.1016/j.injury.2019.03.023 - Ledbury K, Holdsworth L, Robathan M et al. (2019). Developing Undergraduate Trauma Education Through aStudent Led Co-Curriculum Model. BRITISH JOURNAL OF SURGERY 106130-130.
- Wohlgemut JM, Davies J, Aylwin C et al. (2018). Functional inclusivity of trauma networks: a pilot study of the North West London Trauma Network. Journal of Surgical Research 231201-209.
10.1016/j.jss.2018.05.045 - Vinjevoll O-P, Uleberg O, Cole E (2018). Evaluating the ability of a trauma team activation tool to identify severe injury: a multicentre cohort study. Scand J Trauma Resusc Emerg Med 26, (1) 63-.
10.1186/s13049-018-0533-y - Adams RDF, Cole E, Brundage SI et al. (2018). Beliefs and expectations of rural hospital practitioners towards a developing trauma system: A qualitative case study. Injury 49, (6) 1070-1078.
10.1016/j.injury.2018.03.025 - Shepherd JM, Cole E, Brohi K (2016). Contemporary patterns of multiple organ dysfunction in trauma. Shock .
10.1097/SHK.0000000000000779 - Whiting D, Cole E (2016). Developing a trauma care syllabus for intensive care nurses in the United Kingdom: A Delphi study. Intensive Crit Care Nurs 3649-57.
10.1016/j.iccn.2016.03.006 - Cole E, Lecky F, West A et al. (2016). The impact of a pan-regional inclusive trauma system on quality of care. Annals of Surgery 264, (1) 188-194.
10.1097/SLA.0000000000001393 - Manson J, Cole E, De’Ath HD et al. (). Early changes within the lymphocyte population are associated with the development of multiple organ dysfunction syndrome in trauma patients. Critical Care 20, (1) .
10.1186/s13054-016-1341-2 - Heim C, Cole E, West A et al. (2016). Survival prediction algorithms miss significant opportunities for improvement if used for case selection in trauma quality improvement programs. Injury .
10.1016/j.injury.2016.05.042 - Cole E (2015). How regional trauma systems improve outcomes. Emerg Nurse 23, (6) 24-29.
10.7748/en.23.6.24.s23 - Shepherd JM, Cole E, Brohi K (2015). T-5: PATTERNS OF MULTI-ORGAN DYSFUNCTION IN SEVERELY INJURED PATIENTS WITH HAEMORRHAGE. Shock 44 Suppl 221-.
10.1097/01.shk.0000472070.23771.ef - Zinchenko R, Cole E, Glasgow S et al. (2015). Mild, moderate or severe lung injury after trauma: What are the early predictors?. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 23, (2) .
10.1186/1757-7241-23-S2-A8 - Perkins ZB, Yet B, Glasgow S et al. (2015). Meta-analysis of prognostic factors for amputation following surgical repair of lower extremity vascular trauma. British Journal of Surgery 102, (5) 436-450.
10.1002/bjs.9689 - Cole E, Davenport R, Willett K et al. (2015). Tranexamic acid use in severely injured civilian patients and the effects on outcomes: a prospective cohort study. Ann Surg 261, (2) 390-394.
10.1097/SLA.0000000000000717 - Cole E, Davenport R (2015). Early tranexamic acid use in trauma haemorrhage: Why do we give it and which patients benefit most?. International Emergency Nursing 23, (1) 38-41.
10.1016/j.ienj.2014.03.004 - Cole E, Davenport R (2015). Early tranexamic acid use in trauma haemorrhage: why do we give it and which patients benefit most?. Int Emerg Nurs 23, (1) 38-41.
10.1016/j.ienj.2014.03.004 - Perkins ZB, Yet B, Glasgow S et al. (2015). Meta-analysis of prognostic factors for amputation following surgical repair of lower extremity vascular trauma. British Journal of Surgery .
10.1002/bjs.9689 - Shepherd JM, Cole E, Brohi K (2015). PATTERNS OF MULTI-ORGAN DYSFUNCTION IN SEVERELY INJURED PATIENTS WITH HAEMORRHAGE. SHOCK 4421-21.
- Cole E, Davenport R, Willett K et al. (2014). The burden of infection in severely injured trauma patients and the relationship with admission shock severity. Journal of Trauma and Acute Care Surgery 76, (3) 730-735.
10.1097/TA.0b013e31829fdbd7 - Cole E, Davenport R, Willett K et al. (2014). The burden of infection in severely injured trauma patients and the relationship with admission shock severity. J Trauma Acute Care Surg 76, (3) 730-735.
10.1097/TA.0b013e31829fdbd7 - Hoffman K, Cole E, Playford ED et al. (2014). Health outcome after major trauma: what are we measuring?. PLoS One 9, (7) e103082-.
10.1371/journal.pone.0103082 - Crossan L, Cole E (2014). NURSING CHALLENGES WITH A SEVERELY INJURED PATIENT IN CRITICAL CARE: THE IMPORTANCE OF HYPOTHERMIA MITIGATION Reply. NURSING IN CRITICAL CARE 19, (1) 51-51.
10.1111/nicc.12072 - Cole EM, West A, Davenport R et al. (2013). Can residents be effective trauma team leaders in a major trauma centre?. Injury 44, (1) 18-22.
10.1016/j.injury.2011.09.020 - Cole E, Davenport R, De'Ath H et al. (2013). Coagulation system changes associated with susceptibility to infection in trauma patients. J Trauma Acute Care Surg 74, (1) 51-57.
10.1097/TA.0b013e3182788b0f - Khan S, Raza I, Davenport R et al. (2013). MAJOR HEMORRHAGE PROTOCOLS HAVE A LIMITED EFFECT ON TRAUMA-INDUCED COAGULOPATHY. SHOCK 4034-34.
- Manson J, Cooper S, West A et al. (2013). Major trauma and urban cyclists: physiological status and injury profile. Emerg Med J 30, (1) 32-37.
10.1136/emermed-2011-200966 - Hoffman K, West A, Nott P et al. (2013). Measuring acute rehabilitation needs in trauma: Preliminary evaluation of the Rehabilitation Complexity Scale. Injury 44, (1) 104-109.
10.1016/j.injury.2011.11.001 - Hoffman K, West A, Nott P et al. (2013). Measuring acute rehabilitation needs in trauma: preliminary evaluation of the Rehabilitation Complexity Scale. Injury 44, (1) 104-109.
10.1016/j.injury.2011.11.001 - Crossan L, Cole E (2013). Nursing challenges with a severely injured patient in critical care. NURSING IN CRITICAL CARE 18, (5) 236-244.
10.1111/nicc.12019 - Willink M, Khan S, Cole E et al. (2013). OUTCOMES FOLLOWING TRAUMA HEMORRHAGE. SHOCK 4028-29.
- Cole E, Davenport R, Glasgow S et al. (2013). TRANEXAMIC ACID USE IN SHOCKED SEVERELY INJURED PATIENTS AND THE EFFECTS ON OUTCOMES. SHOCK 4021-21.
- Brohi K, Cole E, Hoffman K (2011). Improving outcomes in the early phases after major trauma. Curr Opin Crit Care 17, (5) 515-519.
10.1097/MCC.0b013e32834a9353 - Cole E, Crichton N (2006). The culture of a trauma team in relation to human factors. J Clin Nurs 15, (10) 1257-1266.
10.1111/j.1365-2702.2006.01566.x - Bradbury G, Cole E, Cranston C et al. (2005). Dealing with disaster. Nurs Manag (Harrow) 12, (5) 12-17.