Dr Elaine Cole PhD, MSc, BSc, RN

Director of Research and Innovation, Pan London Major Trauma System/ Senior Lecturer Trauma Sciences

Research 

I am the Director of Research and Innovation for the pan London Major Trauma System. Within this role I work with clinical, academic and managerial staff within the four major trauma networks and pre hospital providers in the London Major Trauma System to support the development of innovation, collaborative research and education across the system. Trauma systems are relatively new to the UK and I co-led the evaluation of the London Trauma System (ELOTS) which reported improvements in care quality and patient outcomes since the system was introduced in 2010. 

My main research interests are investigating the predictors and phenotypes of contemporary multiple organ dysfunction (MODS) after major trauma, and the impact of severe injury on older people. In 2016, I led a national point prevalence study called ORDIT (Organ Dysfunction in Trauma), which involved all Major Trauma Centres in England, Wales and Scotland. 

I am the Chief Investigator for the pan-London Dunhill Medical Trust funded study called MODET. The study was carried out by research teams at the four London Major Trauma Centres and is investigating the characteristics, predictors and outcomes of MODS in severely injured older patients. This important research will help us better understand needs of and plan the care for an increasing elderly major trauma population.

Teaching/Academic

I am a Senior lecturer in Trauma Sciences within the Blizard Institute. My main responsibilities lie within for the MSc in Trauma Sciences where I lead the dissertation project year and the research module. This international online MSc provides its multi-professional students with the opportunity to enhance their knowledge about all aspects of trauma care in a virtual, interactive format, with access to many of the global leaders in clinical trauma management. Within my role I supervise MSc and PhD students, supporting their research projects and publications.

I also co-lead the Trauma Sciences and Care of the Injured Patient Programme (TSCIPP).  This undergraduate SSC provides students with the unique opportunity to gain professional experience in trauma care and clinical research through a structured four-year programme with embedded placements within multidisciplinary teams at Barts Health and the Centre for Trauma Sciences.

Key publications:

The Evolution of Initial-Hemostatic Resuscitation and the Void of Post-Hemostatic Resuscitation.Braasch MC, Turco LM, Cole E, Brohi K, Winfield RD. J Trauma Acute Care Surg. 2020 Jan 24. doi: 10.1097/TA.0000000000002576. [Epub ahead of print] No abstract available. PMID: 31985554

The Changing Epidemiology of Serious Trauma in the Elderly Population: An Increasing Concern of a Tertiary Hospital in Singapore. Go KT, Cheng JY, Seah X, Goh MH, Teo LT, Cole E. Ann Acad Med Singapore. 2019 Nov;48(11):354-362. PMID: 31960015

Targeted prevention of road traffic deaths in Greece: a multifactorial 5-year census-based study. Anagnostou E, Cole E. Eur J Trauma Emerg Surg. 2020 Jan 2. doi: 10.1007/s00068-019-01290-3. [Epub ahead of print]. PMID: 31897511

A Decade of Damage Control Resuscitation: New Transfusion Practice, New Survivors, New Directions.  Cole E, Weaver A, Gall L, West A, Nevin D, Tallach R, O’Neill B, Lahiri S, Allard S, Tai N, Davenport R, Green L, Brohi K.  Ann Surg. 2019 Oct 22. doi: 10.1097/SLA.0000000000003657

Multiple Organ Dysfunction after Trauma: Contemporary Subtypes of Severity and Recovery. Cole E, Gillespie S, Vulliamy P, Brohi K. Br J Surg. 2019 Nov 6. doi: 10.1002/bjs.11361.

Timing and methods of frailty assessments in geriatric trauma patients: A Systematic Review.Cubitt M, Downie E, Shakerian R, Lange PW, Cole E. Injury. 2019 Jul 24. pii: S0020-1383(19)30425-5. doi: 10.1016/j.injury.2019.07.026.

Delivering trauma mastery with an international trauma masters. Schyma BM, Cole E, Wren SM, Brohi K, Brundage SI. Injury. 2019 Apr;50(4):877-882. doi: 10.1016/j.injury.2019.03.023. Epub 2019 Mar 22. PMID: 30935745

Functional inclusivity of trauma networks: a pilot study of the North West London Trauma Network. Wohlgemut JM, Davies J, Aylwin C, Morrison JJ, Cole E, Batrick N, Brundage SI, Jansen JO. J Surg Res. 2018 Nov; 231:201-209. doi: 10.1016/j.jss.2018.05.045. Epub 2018 Jun 21. PMID: 30278930

Evaluating the ability of a trauma team activation tool to identify severe injury: a multicenter cohort study. Vinjevoll OP, Uleberg O, Cole E. Scand J Trauma Resusc Emerg Med. 2018 Aug 10; 26(1):63. doi: 10.1186/s13049-018-0533-y. PMID: 30097047

Beliefs and expectations of rural hospital practitioners towards a developing trauma system: A qualitative case study. Adams RDF, Cole E, Brundage SI, Morrison Z, Jansen JO. Injury. 2018 Mar 22. pii: S0020-1383(18)30137-2. doi: 10.1016/j.injury.2018.03.025.

Shepherd JM, Cole E, Brohi K. Contemporary patterns of multiple organ dysfunction in trauma.  Shock, 2017 Apr;47(4):429-435.

Manson J, Cole E, De'Ath HD, Vulliamy P, Meier U, Pennington D, Brohi K.Early changes within the lymphocyte population are associated with the development of multiple organ dysfunction syndrome in trauma patients.  Crit Care. 2016 Jun 7;20(1):176. 

Cole E, Davenport R, Willett K, Brohi K. Tranexamic acid use in severely injured civilian patients and the effects on outcomes. Ann Surg. 2015 Feb; 261(2):390-4.

Cole E, Davenport R, Willett K, Brohi K. The burden of infection in severely injured trauma patients and the relationship with admission shock severity. J Trauma Acute Care Surg. 2014 Mar; 76(3):730-5.

Cole E, Davenport R, De'Ath H, Manson J, Brockamp T, Brohi K. Coagulation system changes associated with susceptibility to infection in trauma patients. J Trauma Acute Care Surg. 2013 Jan; 74(1):51-7; discussion 57-8.

Contact

email: e.cole@qmul.ac.uk 
Tel: +44 (0) 203 594 0731

  • Braasch MC, Turco LM, Cole E et al. (2020). The Evolution of Initial-Hemostatic Resuscitation and the Void of Post-Hemostatic Resuscitation. J Trauma Acute Care Surg .
    10.1097/TA.0000000000002576
  • Anagnostou E, Cole E (2020). Targeted prevention of road traffic deaths in Greece: a multifactorial 5-year census-based study. Eur J Trauma Emerg Surg .
    10.1007/s00068-019-01290-3
  • COLE ELAINE, Gillespie S, Vulliamy P et al. (). Multiple organ dysfunction after trauma. British Journal of Surgery .
    10.1002/bjs.11361
  • Cubitt M, Downie E, Shakerian R et al. (2019). Timing and methods of frailty assessments in geriatric trauma patients: A systematic review. Injury 50, (11) 1795-1808.
    10.1016/j.injury.2019.07.026
  • Cole E, Weaver A, Gall L et al. (2019). A Decade of Damage Control Resuscitation: New Transfusion Practice, New Survivors, New Directions. Ann Surg .
    10.1097/SLA.0000000000003657
  • Schyma BM, Cole E, Wren SM et al. (2019). Delivering trauma mastery with an international trauma masters. Injury 50, (4) 877-882.
    10.1016/j.injury.2019.03.023
  • Wohlgemut JM, Davies J, Aylwin C et al. (2018). Functional inclusivity of trauma networks: a pilot study of the North West London Trauma Network. Journal of Surgical Research 231201-209.
    10.1016/j.jss.2018.05.045
  • Vinjevoll O-P, Uleberg O, Cole E (2018). Evaluating the ability of a trauma team activation tool to identify severe injury: a multicentre cohort study. Scand J Trauma Resusc Emerg Med 26, (1) 63-.
    10.1186/s13049-018-0533-y
  • Adams RDF, Cole E, Brundage SI et al. (2018). Beliefs and expectations of rural hospital practitioners towards a developing trauma system: A qualitative case study. Injury 49, (6) 1070-1078.
    10.1016/j.injury.2018.03.025
  • Shepherd JM, Cole E, Brohi K (2016). Contemporary patterns of multiple organ dysfunction in trauma. Shock .
    10.1097/SHK.0000000000000779
  • Whiting D, Cole E (2016). Developing a trauma care syllabus for intensive care nurses in the United Kingdom: A Delphi study. Intensive Crit Care Nurs 3649-57.
    10.1016/j.iccn.2016.03.006
  • Cole E, Lecky F, West A et al. (2016). The impact of a pan-regional inclusive trauma system on quality of care. Annals of Surgery 264, (1) 188-194.
    10.1097/SLA.0000000000001393
  • Manson J, Cole E, De┬┐Ath HD et al. (). Early changes within the lymphocyte population are associated with the development of multiple organ dysfunction syndrome in trauma patients. Critical Care 20, (1) .
    10.1186/s13054-016-1341-2
  • Heim C, Cole E, West A et al. (2016). Survival prediction algorithms miss significant opportunities for improvement if used for case selection in trauma quality improvement programs. Injury .
    10.1016/j.injury.2016.05.042
  • Cole E (2015). How regional trauma systems improve outcomes. Emerg Nurse 23, (6) 24-29.
    10.7748/en.23.6.24.s23
  • Shepherd JM, Cole E, Brohi K (2015). PATTERNS OF MULTI-ORGAN DYSFUNCTION IN SEVERELY INJURED PATIENTS WITH HAEMORRHAGE. SHOCK 4421-21.
  • Shepherd JM, Cole E, Brohi K (2015). T-5: PATTERNS OF MULTI-ORGAN DYSFUNCTION IN SEVERELY INJURED PATIENTS WITH HAEMORRHAGE. Shock 44 Suppl 221-.
    10.1097/01.shk.0000472070.23771.ef
  • Zinchenko R, Cole E, Glasgow S et al. (2015). Mild, moderate or severe lung injury after trauma: What are the early predictors?. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 23, (2) .
    10.1186/1757-7241-23-S2-A8
  • Perkins ZB, Yet B, Glasgow S et al. (2015). Meta-analysis of prognostic factors for amputation following surgical repair of lower extremity vascular trauma. British Journal of Surgery 102, (5) 436-450.
    10.1002/bjs.9689
  • Cole E, Davenport R, Willett K et al. (2015). Tranexamic acid use in severely injured civilian patients and the effects on outcomes: a prospective cohort study. Ann Surg 261, (2) 390-394.
    10.1097/SLA.0000000000000717
  • Cole E, Davenport R (2015). Early tranexamic acid use in trauma haemorrhage: Why do we give it and which patients benefit most?. International Emergency Nursing 23, (1) 38-41.
    10.1016/j.ienj.2014.03.004
  • Cole E, Davenport R (2015). Early tranexamic acid use in trauma haemorrhage: why do we give it and which patients benefit most?. Int Emerg Nurs 23, (1) 38-41.
    10.1016/j.ienj.2014.03.004
  • Perkins ZB, Yet B, Glasgow S et al. (2015). Meta-analysis of prognostic factors for amputation following surgical repair of lower extremity vascular trauma. British Journal of Surgery .
    10.1002/bjs.9689
  • Cole E, Davenport R, Willett K et al. (2014). The burden of infection in severely injured trauma patients and the relationship with admission shock severity. Journal of Trauma and Acute Care Surgery 76, (3) 730-735.
    10.1097/TA.0b013e31829fdbd7
  • Cole E, Davenport R, Willett K et al. (2014). The burden of infection in severely injured trauma patients and the relationship with admission shock severity. J Trauma Acute Care Surg 76, (3) 730-735.
    10.1097/TA.0b013e31829fdbd7
  • Hoffman K, Cole E, Playford ED et al. (2014). Health outcome after major trauma: what are we measuring?. PLoS One 9, (7) e103082-.
    10.1371/journal.pone.0103082
  • Crossan L, Cole E (2014). NURSING CHALLENGES WITH A SEVERELY INJURED PATIENT IN CRITICAL CARE: THE IMPORTANCE OF HYPOTHERMIA MITIGATION Reply. NURSING IN CRITICAL CARE 19, (1) 51-51.
    10.1111/nicc.12072
  • Khan S, Raza I, Davenport R et al. (2013). MAJOR HEMORRHAGE PROTOCOLS HAVE A LIMITED EFFECT ON TRAUMA-INDUCED COAGULOPATHY. SHOCK 4034-34.
  • Crossan L, Cole E (2013). Nursing challenges with a severely injured patient in critical care. NURSING IN CRITICAL CARE 18, (5) 236-244.
    10.1111/nicc.12019
  • Willink M, Khan S, Cole E et al. (2013). OUTCOMES FOLLOWING TRAUMA HEMORRHAGE. SHOCK 4028-29.
  • Cole E, Davenport R, Glasgow S et al. (2013). TRANEXAMIC ACID USE IN SHOCKED SEVERELY INJURED PATIENTS AND THE EFFECTS ON OUTCOMES. SHOCK 4021-21.
  • Cole EM, West A, Davenport R et al. (2013). Can residents be effective trauma team leaders in a major trauma centre?. Injury 44, (1) 18-22.
    10.1016/j.injury.2011.09.020
  • Cole E, Davenport R, De'Ath H et al. (2013). Coagulation system changes associated with susceptibility to infection in trauma patients. J Trauma Acute Care Surg 74, (1) 51-57.
    10.1097/TA.0b013e3182788b0f
  • Manson J, Cooper S, West A et al. (2013). Major trauma and urban cyclists: physiological status and injury profile. Emerg Med J 30, (1) 32-37.
    10.1136/emermed-2011-200966
  • Hoffman K, West A, Nott P et al. (2013). Measuring acute rehabilitation needs in trauma: Preliminary evaluation of the Rehabilitation Complexity Scale. Injury 44, (1) 104-109.
    10.1016/j.injury.2011.11.001
  • Hoffman K, West A, Nott P et al. (2013). Measuring acute rehabilitation needs in trauma: preliminary evaluation of the Rehabilitation Complexity Scale. Injury 44, (1) 104-109.
    10.1016/j.injury.2011.11.001
  • Brohi K, Cole E, Hoffman K (2011). Improving outcomes in the early phases after major trauma. Curr Opin Crit Care 17, (5) 515-519.
    10.1097/MCC.0b013e32834a9353
  • Cole E, Crichton N (2006). The culture of a trauma team in relation to human factors. J Clin Nurs 15, (10) 1257-1266.
    10.1111/j.1365-2702.2006.01566.x
  • Bradbury G, Cole E, Cranston C et al. (2005). Dealing with disaster. Nurs Manag (Harrow) 12, (5) 12-17.
 



 

 

 

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