Dr Jordi Lopez Tremoleda
Experimental Models Manager
As a veterinarian with an extensive breath of knowledge on preclinical research, with a PhD in biomedical sciences, I manage the core unit to develop, validate and standardise experimental models for effective trauma translation.
The unit I lead brings together complex models of trauma, haemorrhage, shock, coagulopathy, spinal cord and brain injury to facilitate the full translation of experimental work into the clinics, ensuring animal welfare while providing a unique source of expertise and capability for trauma science.
I am also a Member of the Royal College of Veterinary Surgeons, London (MRCVS).
Research interests:
- To bring together expertise on cutting edge experimental physiology, advanced interventional modelling and technologies such as bioengineering and imaging, to optimise and standardise trauma experimental models.
- To develop an efficacious experimental model pathway to support the development of novel therapeutic.
- To establish complex models integrating neurotrauma, haemorrhage, coagulopathy and organ dysfunction, while working at the interface of collaborative multidisciplinary research groups.
Current projects
- Testing several therapeutic approached to improve the acute clinical management of acute traumatic coagulopathy in a fixed-pressure rodent model of traumatic hemorrhagic shock.
- To development of a model incorporating trauma induced coagulopathy and uncontrolled haemorrhage to enable measurement of a translatable clinical endpoint.
- Implementation of minimally invasive imaging technologies to validate and develop new safety and efficacy readouts for our preclinical trauma models (neuroinflammation, cardiovascular function and tissue perfusion).
- Refinement of welfare assessment and pain management for interventional trauma models.
Other interests
With an MSc in Bioethics , I am very interested in regulatory and ethical aspects related to health and biotechnology issues, with a particular interest in animal welfare, to promote high standards for in vivo research. I am member of the LASA UK and involved in welfare animal research bodies.
Having extensively worked in preclinical imaging, we are very interested in the implementation of forefront imaging modalities in our models, to maximise their translational efficacy and to support the development of new clinical minimally invasive assessment methods and pioneer new biomarkers and biological sensors.
- Gonzalez-Uarquin F, Jirkof P, Lang A et al. (2026). News from the EIC team. Laboratory Animals 60, (2) 129-129.
10.1177/00236772261445336 - Tremoleda JL, Brønstad A, Potschka H et al. (2026). Challenges and expectations on the use of automated home cage monitoring for advancing laboratory animal care and welfare. Laboratory Animals 60, (1) 25-30.
10.1177/00236772251396319 - Singh A, Rigon M, Guo T et al. (2026). TSPO-mediated mitochondrial retrograde signaling primes the microglial NLRP3 inflammasome. Pharmacological Research 226108145-.
10.1016/j.phrs.2026.108145 - Roe E, Bailey SJ, Mackenzie L et al. (2025). Creative pedagogic methods for self-guided embodied thinking and learning about animal research. Wellcome open research 10595-.
10.12688/wellcomeopenres.24930.1 - Lang A, Jirkof P, Sanchez-Morgado J et al. (2025). News from the EIC team. Laboratory Animals 59, (3) 315-315.
10.1177/00236772251338015 - Karp NA, Berdoy M, Gray K et al. (). The Sex Inclusive Research Framework to address sex bias in preclinical research proposals. Nature Communications 16, (1) 3763-.
10.1038/s41467-025-58560-5 - Thaventhiran A, Lopez-Tremoleda J, Thiemermann C (2025). 177 Novel antifibrinolytic therapy to target Acute Traumatic Coagulopathy (ATC) during major traumatic haemorrhage. British Journal of Surgery 112, (Supplement_6) znaf042.011-.
10.1093/bjs/znaf042.011 - Tremoleda J, Jirkof P, Lang A et al. (2024). To our esteemed colleague J-P. Laboratory Animals 58, (6) 510-511.
10.1177/00236772241299289 - Valero-Hernandez E, Tremoleda JL, Michael-Titus AT (). Omega-3 Fatty Acids and Traumatic Injury in the Adult and Immature Brain. Nutrients 16, (23) 4175-.
10.3390/nu16234175 - Tremoleda JL (2024). Our 61st Annual Meeting: An exciting programme is shaping up!. Laboratory Animals 58, (5) 499-499.
10.1177/00236772241279473 - Al-Khateeb ZF, Henson SM, Tremoleda JL et al. (). The Immune Response in Two Models of Traumatic Injury of the Immature Brain. Cells 13, (19) 1612-.
10.3390/cells13191612 - Greenhough B, Tremoleda JL, Kerton A et al. (2024). 8 Commentaries on culturing and sustaining care. 197-220.
10.7765/9781526165770.00016 - Al-Khateeb ZF, Boumenar H, Adebimpe J et al. (2024). The cellular senescence response and neuroinflammation in juvenile mice following controlled cortical impact and repetitive mild traumatic brain injury. Experimental Neurology 374114714-.
10.1016/j.expneurol.2024.114714 - Simpson R, Praditsuktavorn B, Wall J et al. (2023). Myocardial alterations following traumatic hemorrhagic injury. Journal of Trauma and Acute Care Surgery 95, (4) 481-489.
10.1097/ta.0000000000003987 - Gains CC, Giannapoulos A, Zamboulis DE et al. (2023). Development and application of a novel in vivo overload model of the Achilles tendon in rat. Journal of Biomechanics 151111546-.
10.1016/j.jbiomech.2023.111546 - Warner A, Law B, Tremoleda JL (2023). A successful return to in-person LASA Annual Conference 2022. Laboratory Animals 57, (1) 87-88.
10.1177/00236772221149338 - Tremoleda JL, Cederroth C, Jirkof P (2023). Engaging on discussions about the use and the replacement of animals in research with young minds. Laboratory Animals 57, (3) 221-223.
10.1177/00236772221147134 - Tremoleda JL, Blau CW (2023). Chapter 29 Anesthesia for in vivo imaging studies: practical considerations for experimental outcomes and animal welfare. 711-723.
10.1016/b978-0-12-822215-7.00012-3 - Kirtland J, Tremoleda JL, Trivedy C (2024). Traumatic injury patterns in humans from large feline predators: A systematic review and descriptive analysis. Trauma (London, England) 26, (1) 28-42.
10.1177/14604086221123307 - Tremoleda JL (). Reducing the Number of Research Animals: How Imaging Technologies Can Help. Frontiers for Young Minds 10953662-.
10.3389/frym.2022.953662 - Tremoleda JL, Kerton A, Mazhary H et al. (2023). New perspectives for teaching Culture of Care and their strengths and challenges. Laboratory Animals 57, (2) 170-181.
10.1177/00236772221127352 - Perez-Ternero C, Pallier PN, Tremoleda JL et al. (). C-type natriuretic peptide preserves central neurological function by maintaining blood-brain barrier integrity. Frontiers in Molecular Neuroscience 15991112-.
10.3389/fnmol.2022.991112 - Sánchez-Morgado JM, Whitfield L, Tremoleda JL et al. (2023). How to publish a case report in Laboratory Animals?. Laboratory Animals 57, (1) 2-2.
10.1177/00236772221103964 - Sánchez-Morgado JM, Jirkof P, Lang A et al. (2022). Is it time for a ‘Culture of Carers’?. Laboratory Animals 56, (6) 498-498.
10.1177/00236772221102078 - Teoh L, Ihalage AA, Harp S et al. (). Deep learning for behaviour classification in a preclinical brain injury model. PLOS ONE 17, (6) e0268962-.
10.1371/journal.pone.0268962 - Tremoleda JL, Law B (2022). Success for our first Virtual LASA Annual Conference. Laboratory Animals 56, (2) 201-203.
10.1177/00236772221081776 - Lang A, Jirkof P, Mocho J-P et al. (2022). Report from the 11th edition of the World Congress on Alternatives and Animal Use in the Life Sciences (WC11). Laboratory Animals 56, (1) 101-102.
10.1177/00236772211064174 - Jirkof P, Lang A, Mocho JP et al. (2021). Diversity at the core of all our work!. Laboratory Animals 55, (5) 386-386.
10.1177/00236772211049621 - Osman M, Olkun A, Maldonado AM et al. (2021). Parentally deprived juvenile Owl monkeys suffer from long‐term high infection rates but not from altered hair cortisol concentrations nor from stereotypic behaviours. Journal of Medical Primatology 50, (6) 306-312.
10.1111/jmp.12545 - Jirkof P, Lang A, Mocho J-P et al. (2021). Do you want to join our Editorial Board?. Laboratory Animals 55, (3) 202-214.
10.1177/00236772211012841 - Thaventhiran A, Thiemermann C, Brohi K et al. (2021). O1: DISCOVERING NOVEL THERAPEUTICS TO TREAT ACUTE TRAUMATIC COAGULOPATHY (ATC). British Journal of Surgery 108, (Supplement_1) znab117.001-.
10.1093/bjs/znab117.001 - Jirkof P, Sanchez-Morgado J, Tremoleda JL (2021). News from the EIC team. Laboratory Animals 55, (2) 189-189.
10.1177/0023677221999329 - Kerton A, Tremoleda JL (2021). Emotional challenges in our work with laboratory animals: tools that support caring for others and yourself. Animal Technology and Welfare 20, (1) 35-41.
- Jennings M, Berdoy M, Farmer AM et al. (2021). Guiding principles to help deliver the ethics learning outcomes of module 2 for personal licensees. Animal Technology and Welfare 20, (1) 63-72.
- Tremoleda JL, Kerton A (). Teaching a culture of care: Why it matters. Revista de Bioética y Derecho 0, (51) 43-60.
10.1344/rbd2021.51.31130 - Thau-Zuchman O, Svendsen L, Dyall SC et al. (2021). A new ketogenic formulation improves functional outcome and reduces tissue loss following traumatic brain injury in adult mice. Theranostics 11, (1) 346-360.
10.7150/thno.48995 - Praditsuktavorn B, Wall J, Thiemermann C et al. (2020). Rescuing Cardiac Dysfunction Following Traumatic Haemorrhagic Injury. CIRCULATION 142, (24) E496-E497.
- Tremoleda JL, Kerton A (2020). Creating space to build emotional resilience in the animal research community. Lab Animal 49, (10) 275-277.
10.1038/s41684-020-0637-7 - Nandi M, Jackson SK, Macrae D et al. (2020). Rethinking animal models of sepsis – working towards improved clinical translation whilst integrating the 3Rs. Clinical Science 134, (13) 1715-1734.
10.1042/cs20200679 - Topping LM, Thomas BL, Rhys HI et al. (). Targeting Extracellular Vesicles to the Arthritic Joint Using a Damaged Cartilage-Specific Antibody. Frontiers in Immunology 1110-.
10.3389/fimmu.2020.00010 - Praditsuktavorn B, Wall J, Thiemermann C et al. (2020). Rescuing Cardiac Dysfunction Following Traumatic Haemorrhagic Injury. CIRCULATION 142, (24) E496-E497.
- Thau-Zuchman O, Ingram R, Harvey GG et al. (2020). A Single Injection of Docosahexaenoic Acid Induces a Pro-Resolving Lipid Mediator Profile in the Injured Tissue and a Long-Lasting Reduction in Neurological Deficit after Traumatic Brain Injury in Mice. Journal of Neurotrauma 37, (1) 66-79.
10.1089/neu.2019.6420 - Wall J, Naganathar S, Praditsuktavorn B et al. (). RETRACTED: Modeling Cardiac Dysfunction Following Traumatic Hemorrhage Injury: Impact on Myocardial Integrity. Frontiers in Immunology 102774-.
10.3389/fimmu.2019.02774 - Yip PK, Chapman GE, Sillito RR et al. (2019). Studies on long term behavioural changes in group-housed rat models of brain and spinal cord injury using an automated home cage recording system. Journal of Neuroscience Methods 32149-63.
10.1016/j.jneumeth.2019.04.005 - Zuchman OT, Svendsen L, Groenendijk M et al. (2019). A NEW KETOGENIC FORMULATION IMPROVES FUNCTIONAL OUTCOME AND REDUCES TISSUE DAMAGE FOLLOWING TRAUMATIC BRAIN INJURY. JOURNAL OF NEUROTRAUMA 36, (13) A131-A132.
- Thau-Zuchman O, Gomes RN, Dyall SC et al. (2019). Brain Phospholipid Precursors Administered Post-Injury Reduce Tissue Damage and Improve Neurological Outcome in Experimental Traumatic Brain Injury. Journal of Neurotrauma 36, (1) 25-42.
10.1089/neu.2017.5579 - Alvarez K, Lopez-Tremoleda J, Donnan R et al. (2018). Heart rate sensitive optical coherence angiography. 10493104930g-.
10.1117/12.2317602 - Tremoleda JL, Macholl S, Sosabowski JK (2018). Anesthesia and Monitoring of Animals During MRI Studies. 1718423-439.
10.1007/978-1-4939-7531-0_25 - Tremoleda JL, Alvarez K, Aden A et al. (2017). Heart-rate sensitive optical coherence angiography for measuring vascular changes due to posttraumatic brain injury in mice. Journal of Biomedical Optics 22, (12) 121710-121710.
10.1117/1.jbo.22.12.121710 - Tremoleda JL, Watts SA, Reynolds PS et al. (2017). Modeling Acute Traumatic Hemorrhagic Shock Injury. Shock 48, (6) 610-623.
10.1097/shk.0000000000000901 - Luong L, Duckles H, Schenkel T et al. (2016). Heart rate reduction with ivabradine promotes shear stress-dependent anti-inflammatory mechanisms in arteries. Thrombosis and Haemostasis 116, (01) 181-190.
10.1160/th16-03-0214 - Venero JL, Yip PK, Carrillo-Jimenez A et al. (2017). Galectin-3 acts as an early alarmin orchestrating brain immune response and promoting neurodegeneration after traumatic brain injury. GLIA 65E504-E504.
- Chan JMS, Monaco C, Wylezinska-Arridge M et al. (2018). Imaging vulnerable plaques by targeting inflammation in atherosclerosis using fluorescent-labeled dual-ligand microparticles of iron oxide and magnetic resonance imaging. Journal of Vascular Surgery 67, (5) 1571-1583.e3.
10.1016/j.jvs.2017.04.046 - Schrantee A, Tremoleda JL, Wylezinska-Arridge M et al. (). Repeated dexamphetamine treatment alters the dopaminergic system and increases the phMRI response to methylphenidate. PLOS ONE 12, (2) e0172776-.
10.1371/journal.pone.0172776 - Yip PK, Carrillo-Jimenez A, King P et al. (). Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration. Scientific Reports 7, (1) 41689-.
10.1038/srep41689 - Pedrigi RM, Mehta VV, Bovens SM et al. (2016). Influence of shear stress magnitude and direction on atherosclerotic plaque composition. Royal Society Open Science 3, (10) 160588-.
10.1098/rsos.160588 - Tremoleda JL, Thau-Zuchman O, Davies M et al. (2016). In vivo PET imaging of the neuroinflammatory response in rat spinal cord injury using the TSPO tracer [(18)F]GE-180 and effect of docosahexaenoic acid. Eur J Nucl Med Mol Imaging 43, (9) 1710-1722.
10.1007/s00259-016-3391-8 - LOPEZ TREMOLEDA J (2016). In vivo PET imaging of the neuroinflammatory response
in rat spinal cord injury using the TSPO tracer [18F]GE-180
and effect of docosahexaenoic acid. Eur J Nucl Med Mol Imaging .
10.1007/s00259-016-3391-8 - Thau-Zuchman O, Pallier PN, Davies M et al. (2016). A specific multi-nutrient intervention, designed to enhance synapse formation and function, improves functional outcome following traumatic brain injury. BRAIN INJURY 30, (5-6) 679-679.
- Tremoleda JL, Thau-Zuchman O, Davies M et al. (2015). T-14: IN VIVO IMAGING OF NEUROINFLAMMATION IN NEUROTRAUMA PRECLINICAL MODELS: POTENTIAL FOR CLINICAL TRANSLATION. Shock 44 Suppl 224-25.
10.1097/01.shk.0000472079.77136.27 - Tremoleda JL, Sosabowski J (2015). Imaging technologies and basic considerations for welfare of laboratory rodents. Lab Animal 44, (3) 97-105.
10.1038/laban.665 - Tremoleda JL, Thau-Zuchman O, Davies M et al. (2015). IN VIVO IMAGING OF NEUROINFLAMMATION IN NEUROTRAUMA PRECLINICAL MODELS: POTENTIAL FOR CLINICAL TRANSLATION. SHOCK 4424-25.
- Wall JM, Tremoleda JL, Thiemermann C et al. (2015). HEART FATTY ACID BINDING PROTEIN (H-FABP) IS A BIOMARKER OF TRAUMA-INDUCED SECONDARY CARDIAC INJURY IN A PRE-CLINICAL MODEL OF TRAUMA-HAEMORRHAGE. SHOCK 4421-22.
- Tremoleda JL, Sosabowski J (2015). Imaging technologies and basic considerations for welfare of laboratory rodents. LAB ANIMAL 44, (3) 101-109.
- Mehta VV, Pedrigi RM, Bovens SM et al. (2014). Longitudinal predictive analysis of vulnerable plaques in a mouse model of atherosclerosis. Atherosclerosis 237, (2) e11-.
10.1016/j.atherosclerosis.2014.10.066 - Cuhlmann S, Gsell W, Van der Heiden K et al. (2014). In Vivo Mapping of Vascular Inflammation Using the Translocator Protein Tracer 18F-FEDAA1106. Molecular Imaging 13, (6) 7290.2014.00014-.
10.2310/7290.2014.00014 - Guerreiro M, Tremoleda JL, Frith D et al. (2014). Reduction of the natural Activated protein C pathway activity significantly prevents coagulopathy in a murine model of acute traumatic coagulopathy. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 22, (Suppl 1) o6-.
10.1186/1757-7241-22-s1-o6 - Chan JMS, Monaco C, Wylezinska-Arridge M et al. (2014). Imaging of the Vulnerable Carotid Plaque: Biological Targeting of Inflammation in Atherosclerosis Using Iron Oxide Particles and MRI. Journal of Vascular Surgery 59, (5) 1472-.
10.1016/j.jvs.2014.03.246 - Chan JMS, Monaco C, Wylezinska-Arridge M et al. (2014). Imaging of the Vulnerable Carotid Plaque: Biological Targeting of Inflammation in Atherosclerosis using Iron Oxide Particles and MRI. European Journal of Vascular and Endovascular Surgery 47, (5) 462-469.
10.1016/j.ejvs.2014.01.017 - Guerreiro ML, Tremoleda JL, Thiemermann C et al. (2014). REDUCTION OF NATURAL ACTIVATED PROTEIN C PREVENTS COAGULOPATHY IN A PRECLINICAL ANIMAL MODEL OF ACUTE TRAUMATIC COAGULOPATHY. SHOCK 4151-51.
- Schrantee A, Tremoleda JL, Wylezinska-Arridge M et al. (2013). P.1.i.016 Amphetamine pretreatment alters the response to a methylphenidate challenge: a pharmacological magnetic resonance imaging study. European Neuropsychopharmacology 23s272-.
10.1016/s0924-977x(13)70424-3 - Kazakidi A, Wylezinska M, Bohraus Y et al. (2010). Numerical Modelling of Blood Flow in the Mouse Aortic Arch Using Inflow Velocities Obtained by Phase-Contrast MRI. 555-556.
10.1115/sbc2010-19270 - Lopez-Tremoleda J, Gsell W (2013). The use of contrast agents to enhance soft-tissue imaging using micro-CT in laboratory rodents. Animal Technology and Welfare 12, (1) 59-62.
- Cristante E, McArthur S, Mauro C et al. (2013). Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications. Proc Natl Acad Sci U S A 110, (3) 832-841.
10.1073/pnas.1209362110 - Stasiuk GJ, Smith H, Wylezinska-Arridge M et al. (2013). Gd 3+ cFLFLFK conjugate for MRI: a targeted contrast agent for FPR1 in inflammation. Chemical Communications 49, (6) 564-566.
10.1039/c2cc37460a - Tremoleda JL, Khan NS, Mann V et al. (2012). Assessment of a preclinical model for studying the survival and engraftment of human stem cell derived osteogenic cell populations following orthotopic implantation. Journal of Musculoskeletal and Neuronal Interactions 12, (4) 241-253.
- Tremoleda JL, Kerton A, Gsell W (2012). Anaesthesia and physiological monitoring during in vivo imaging of laboratory rodents: considerations on experimental outcomes and animal welfare. EJNMMI Research 2, (1) 44-.
10.1186/2191-219x-2-44 - Hawkins P, Burn C, Deacon R et al. (2012). Report of the 2011 RSPCA/UFAW Rodent Welfare Group meeting - Harms and benefits of new technologies. Animal Technology and Welfare 11, (2) 95-120.
- Van Doormaal MA, Kazakidi A, Wylezinska M et al. (2012). Haemodynamics in the mouse aortic arch computed from MRI-derived velocities at the aortic root. Journal of The Royal Society Interface 9, (76) 2834-2844.
10.1098/rsif.2012.0295 - Tremoleda J, de Lecuona I, Harding S (2012). From which source?. 113-114.
10.1201/b11937-12 - Tremoleda JL, de Lecuona I, Harding SE (2012). Technical and Bioethical Challenges Associated with using Stem Cells for Research and Therapy. 154-188.
10.1201/b11937-11 - Bouet V, Klomp A, Freret T et al. (2012). Age-dependent effects of chronic fluoxetine treatment on the serotonergic system one week following treatment. Psychopharmacology (Berl) 221, (2) 329-339.
10.1007/s00213-011-2580-1 - Klomp A, Tremoleda JL, Schrantee A et al. (). The Use of Pharmacological-challenge fMRI in Pre-clinical Research: Application to the 5-HT System. Journal of Visualized Experiments , (62) 3956-.
10.3791/3956 - Seyfried F, Lannoo M, Gsell W et al. (2012). Roux-en-Y Gastric Bypass in Mice—Surgical Technique and Characterisation. Obesity Surgery 22, (7) 1117-1125.
10.1007/s11695-012-0661-9 - Tremoleda JL (). Comentarios sobre la Directiva Europea 2010/63/EU para la proteccin de animales de laboratorio. Revista de Bioética y Derecho , (24) 61-72.
10.4321/s1886-58872012000100006 - Stuckey DJ, Tremoleda JL, Mcsweeney S et al. (2012). Systematic evaluation of 2D versus M-mode echocardiography in mice, compared to ex vivo and in vivo MRI. CARDIOVASCULAR RESEARCH 93S90-S90.
- Tremoleda JL, de Lecuona I, Harding SE (2012). Technical and bioethical challenges associated with using stem cells for research and therapy. 154-188.
10.1201/b11937 - Klomp A, Tremoleda JL, Wylezinska M et al. (2012). Lasting effects of chronic fluoxetine treatment on the late developing rat brain: Age-dependent changes in the serotonergic neurotransmitter system assessed by pharmacological MRI. NeuroImage 59, (1) 218-226.
10.1016/j.neuroimage.2011.07.082 - Tremoleda JL, Khalil M, Gompels LL et al. (2011). Imaging technologies for preclinical models of bone and joint disorders. EJNMMI Research 1, (1) 11-.
10.1186/2191-219x-1-11 - Song W, Dyer E, Stuckey DJ et al. (2011). Molecular Mechanism of the E99K Mutation in Cardiac Actin (ACTC Gene) That Causes Apical Hypertrophy in Man and Mouse*. Journal of Biological Chemistry 286, (31) 27582-27593.
10.1074/jbc.m111.252320 - Khalil MM, Tremoleda JL, Bayomy TB et al. (2011). Molecular SPECT Imaging: An Overview. International Journal of Molecular Imaging 2011, (1) 796025-.
10.1155/2011/796025 - Cuhlmann S, Van der Heiden K, Saliba D et al. (2011). Disturbed Blood Flow Induces RelA Expression via c-Jun N-Terminal Kinase 1. Circulation Research 108, (8) 950-959.
10.1161/circresaha.110.233841 - Gsell W, Cuhlmann S, Van der Heiden K et al. (2011). 18FEDAA is a more specific probe than 18FDG for imaging vascular inflammation. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 38S210-S210.
- Tremoleda JL, Khalil M, Gsell W et al. (2011). The use of micro-computed tomography to study bone changes in a preclinical model of Osteoarthritis. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 38S418-S418.
- Khan NS, Tremoleda JL, Riahi S et al. (2009). 488 POTENTIAL OF HUMAN EMBRYONIC STEM CELL-DERIVED CHONDROGENIC CELLS TO REPAIR AN ARTICULAR DEFECT. Osteoarthritis and Cartilage 17s262-.
10.1016/s1063-4584(09)60509-4 - Khan NS, Tremoleda JL, Riahi S et al. (2009). Regenerative properties of human embryonic stem cell-derived chondrogenic cells in an articular defect. European Cells and Materials 18, (SUPPL. 1) 48-.
- Tremoleda JL, Forsyth NR, Khan NS et al. (2008). Bone Tissue Formation from Human Embryonic Stem Cells In Vivo. Cellular Reprogramming 10, (1) 119-132.
10.1089/clo.2007.0r36 - Dell'Aquila ME, Albrizio M, Guaricci AC et al. (2008). Expression and localization of the µ‐opioid receptor (MOR) in the equine cumulus–oocyte complex and its involvement in the seasonal regulation of oocyte meiotic competence. Molecular Reproduction and Development 75, (8) 1229-1246.
10.1002/mrd.20869 - Moussa M, Tremoleda JL, Duchamp G et al. (2004). Evaluation of viability and apoptosis in horse embryos stored under different conditions at 5 °C. Theriogenology 61, (5) 921-932.
10.1016/s0093-691x(03)00280-2 - Tremoleda JL, Stout TAE, Gadella BM et al. (2004). 286 SPERM–OOCYTE INTERACTION DURING IN VITRO FERTILIZATION IN THE HORSE. Reproduction Fertility and Development 16, (2) 263-263.
10.1071/rdv16n1ab286 - Tremoleda JL, Stout TAE, Lagutina I et al. (2003). Effects of In Vitro Production on Horse Embryo Morphology, Cytoskeletal Characteristics, and Blastocyst Capsule Formation. Biology of Reproduction 69, (6) 1895-1906.
10.1095/biolreprod.103.018515 - Li X, Tremoleda JL, Allen WR (2003). Effect of the number of passages of fetal and adult fibroblasts on nuclear remodelling and first embryonic division in reconstructed horse oocytes after nuclear transfer. Reproduction 125, (4) 535-542.
10.1530/rep.0.1250535 - Tremoleda JL, Tharasanit T, Van Tol HTA et al. (2003). Effects of follicular cells and FSH on the resumption of meiosis in equine oocytes matured in vitro. Reproduction 125, (4) 565-577.
10.1530/rep.0.1250565 - Tremoleda JL, van Haeften T, Stout TAE et al. (2003). Cytoskeleton and Chromatin Reorganization in Horse Oocytes Following Intracytoplasmic Sperm Injection: Patterns Associated with Normal and Defective Fertilization. Biology of Reproduction 69, (1) 186-194.
10.1095/biolreprod.102.012823 - (2002). Mid-diestrous GnRH-analogue administration does not suppress the luteolytic mechanism in mares. Theriogenology 58, (2-4) 567-570.
10.1016/s0093-691x(02)00860-9 - (2002). Reorganisation of the cytoskeleton and chromatin in horse oocytes following intracytoplasmic sperm injection. Theriogenology 58, (2-4) 697-700.
10.1016/s0093-691x(02)00794-x - CHENG, FAZELI, VOORHOUT et al. (1998). Progesterone in mare follicular fluid induces the acrosome reaction in stallion spermatozoa and enhances in vitro binding to the zona pellucida. International Journal of Andrology 21, (2) 57-66.
10.1046/j.1365-2605.1998.00096.x - Marescalchi O, Scali V (2001). New DAPI and fish findings on egg maturation processes in related hybridogenetic and parthenogenetic Bacillus hybrids (insecta, phasmatodea). Molecular Reproduction and Development 60, (2) 270-276.
10.1002/mrd.1087 - Tremoleda JL, Schoevers EJ, Stout TAE et al. (2001). Organisation of the cytoskeleton during in vitro maturation of horse oocytes. Molecular Reproduction and Development 60, (2) 260-269.
10.1002/mrd.1086 - Saballs P, Aregall S, Pallarés E et al. (1993). Salmonella typhimurium as the causal agent of pulmonary cavitations. Enfermedades Infecciosas y Microbiología Clínica 11, (2) 93-96.
- San L, Tremoleda J, Ollé JM et al. (1989). Prevalence of buprenorphine use by heroin addicts undergoing treatment. Medicina Clínica 93, (17) 645-648.
- Sus Z, Verma I, Khan SH et al. (). Brief, repeated isoflurane anaesthesia elicits sex-dependent behavioural, cerebrovascular, and microglial alterations in mice. .
10.64898/2026.02.11.705306 - Roe E, Bailey SJ, Mackenzie L et al. (). Creative pedagogic methods for self-guided embodied thinking and learning about animal research. .
10.12688/wellcomeopenres.24930.1 - Becker IC, Smith EJ, Dark N et al. (). Megakaryocyte activation and mobilization from the bone marrow in response to trauma and hemorrhagic shock in mice. .
10.64898/2026.02.10.704825 - Singh A, Rigon M, Caldeira MG et al. (). Mitochondria drive microglial NRLP3 inflammasome activation via TSPO. .
10.1101/2024.03.18.585507 - Osman M, Olkun A, Maldonado AM et al. (). Rejection in early life is associated with high and long-lasting stress and higher incidence of infections in owl monkeys. .
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