Miss Joanna Manson

Surgeon, Post-doctoral researcher and Fulbright Scholar, Jo’s interest is the innate immune response to traumatic injury and its influence on patient recovery. Her PhD work identified an association between early immune cell responses and the development of multiple organ failure. This initiated new lines of investigation for the group, in the search for new therapeutic strategies to optimise trauma patient recovery.

Jo trained at Imperial College (St Mary’s Medical School) London and continues her General and Vascular Surgery training in the London Deanery.  She developed an interest in trauma care during medical school and recognised the need for improved provision of trauma services in the UK. She spent six months working in a trauma unit in Cape Town, South Africa to gain additional trauma experience and holds a PhD in Trauma Science. During her Fulbright Year, Jo worked at the Level 1 trauma centre UPMC Presbyterian, in Pittsburgh USA, conducting research in Professor Tim Billiar’s Lab. Using a murine model, she investigated the innate-like lymphocytes and their response to traumatic injury. This again opened up new lines for investigation and collaboration.


Inaugural RCS of England Fulbright Scholars Award 2012-13

RCS of England & Philip King Charitable Trust Research Fellowship 2011-12

Teaching & Public Engagement

Jo is a tutor for the department’s Msc in Trauma Sciences and an ATLS Instructor. She has successfully mentored MSc , BSc and medical student projects. She now supervises a PhD student. A supporter of public engagement, she helped devise and deliver exhibits for The Royal Society Summer Fair, The Big Bang in Birmingham and The Moscow Science Exhibition 2011. 

Personal interests

Outside of work, Jo enjoys dancing, swimming, yoga, cycling and kite-surfing. She has travelled extensively and has a young family.

Contact: joanna.manson@gmail.com

Cole E, Davenport R, De'Ath H, Manson J, Brockamp T, Brohi K.  Coagulation system changes associated with susceptibility to infection in trauma patients. J Trauma Acute Care Surg. 2013 Jan;74(1):51-7

Henry D De’Ath, Joanna Manson, Ross Davenport, Simon Glasgow, Ian Renfrew, L Ceri Davies, Raskesh Uppal and Karim Brohi. Trauma Induced secondary cardiac injury is associated with hyperactute elevations in inflammatory cytokines. Shock 2013;39(5):415-420.

Simon T Abrams, Nan Zhang, Joanna Manson, Tingting Liu, Caroline Dart, Florence Baluwa, Susan Siyu Wang, Karim Brohi, Anja Kipar, Weiping Yu, GuozhengWang and Cheng-Hock Toh. Circulating histones are mediators of trauma-associated lung injury. American Journal of Respiratory and Critical Care Medicine 2013;187(2): 160-169

Raza I, Davenport R, Rourke C, Platton S, Manson J, Spoors C, Khan S, De'ath H, Allard S, Hart D, John Pasi K, Hunt BJ, Stanworth S, Maccallum P, Brohi K. The incidence and magnitude of fibrinolytic activation in trauma patients.  J Thromb Haemost. 2013;11(2):307-14

Davenport R, Manson J, De’Ath H et al. Systemic activation of protein C is a central mechanism of acute traumatic coagulopathy. Submitted to the Journal of Clinical Investigation

Manson J, Cooper S, Cole E, West A, Foster E, NRM Tai. Major trauma and urban cyclists: physiological status and injury profile.  Emerg Med J. 2013 Jan;30(1):32-7

Manson J, Thiemermann C, Brohi K. Trauma alarmins as activators of damage induced inflammation. British Journal of Surgery Trauma Supplement Jan 2012;99(1):12-20

D. De’Ath, C. Rourke, R. Davenport, J. Manson, I. Renfrew, R. Uppal, L. C. Davies & K. Brohi. Clinical and biomarker profile of trauma-induced secondary cardiac injury. British Journal of Surgery June 2012;99(6):689-797 

Davenport R, Manson J, De’Ath H et al. Functional definition and characterisation of Acute Traumatic CoagulopathyCrit care med Dec 2011;39(12):2652-2658

Davenport R, Curry N, Manson J et al.  Haemostatic effects of fresh frozen plasma may be maximal at red cell ratios of 1:2.   J Trauma 2011 Jan;70(1):90-5

Manson J, Ade-Ajayi N. Gastroschisis: a multi-centre comparison of management and outcome. African journal of paediatric surgery 2012;9(1):17-21

Powell-Tuck J, Gosling P, Lobo D, Allison SP …. Manson J... et al. British consensus guidelines on intravenous fluid therapy for adult surgical patients GIFTASUP. October 2006. I participated in the consensus symposium.

Shah J, Munz Y, Manson J, Moorthy K, Darzi A.  Objective assessment of small bowel anastomosis skill in trainee general surgeons and urologists.  World J Surg. 2006 Feb;30(2):248-51

Manson J, Nicol A, Navsaria P.  Tension pneumopericardium: A rare complication in penetrating chest trauma: A case report and review of the literature   Injury Extra 2005 Aug:36(8):349-351

Shah J, Munz Y, Bann S, Manson J, Darzi A.  Evaluation of knot tying at depth between general surgeons and urologists.  Ann R Coll Surg Engl. 2004 Sep;86(5):381-2

Shah J, Manson J, Boyd J.  Recruitment of Urology: A national survey in the UK  Ann R Coll Surg Engl. 2004 May;86(3):186-9

Shah J, Billington R, Manson J, Vale J.  Undergraduate Urology: a survey of current provisions and guidelines for a core curriculum.  BJU International 2001;89:327-330

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