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Professor Karim Brohi

Professor of Trauma Sciences

As head of the Trauma Sciences research team, my time is divided between surgery and science.

As a surgeon, Karim provides care for patients with vascular diseases and traumatic injury. As a scientist, Karim conducts research in the field of Trauma while supervising a range of researchers who are investigating different aspects of traumatic disease. 

In medical practice, trauma specialists use the available evidence to determine and deliver the best patient care. There are many instances where best practice has not been established because medical professionals currently don't fully understand the disease. Karim's aim is to improve the care of trauma patients by increasing our understanding of the disease processes.

Karim studied Medicine at University College Hospital London. At university, Karim also obtained an intercalated BSc in Computer Science and spent a 12-week elective in Trinidad and Tobago. Soon Karim realised that the management of trauma patients in the UK was extremely poor, which fuelled an ambition to improve the standards. Following this, Karim set up the trauma. org resources, which provides education, expert discussion and online support for trauma surgeons worldwide. Having been developed further, AfterTrauma.org has been developed to provide resources and support to patients and their families following a traumatic injury. 

Karim completed several years of training and became qualified in both Anaesthetics and Surgery. Viewed as unusual in many cases, Karim has an extremely useful set of skills for trauma patient management. Karim has worked for the Helicopter Emergency Medical Service (HEMS) in London and spent two years working at a Trauma Hospital in San Francisco. Following this, Karim obtained a Consultant post at The Royal London Hospital and returned to the UK to set up a trauma research department.

Trauma Sciences joined the Centre for Neuroscience in 2008. The centre is housed within the Blizard Institute at Barts and The London School of Medicine and Dentistry. The aim is to improve our understanding of trauma through laboratory experiments and then use those findings to improve patient outcomes by developing new treatment strategies. There collaborations with trauma units within Europe and the USA have been established, along with clinical trials for products designed for use in trauma. Conducting research in emergency surgical conditions is challenging but is essential if we are to make improvements for patients. In the UK, lack of trauma experience and poor organisation of trauma services means that patients are still dying from treatable injuries.

Karim's hope is the future includes specialist trauma centres which provide specialised trauma care from the moment of injury to the end of rehabilitation. Trauma research is an essential component of this process. Karim travels frequently to deliver lectures and teaching. In 2011, he set up an MSc in Trauma Science.

When he is not at work, he enjoys watching movies and enjoying good restaurants. Surgery is a very challenging career but it can also be very rewarding and Karim would encourage anyone who wants to pursue a career in surgery to do so. Trauma has finally been recognised as an important component of surgery in the UK so the future for this specialty is very exciting.

Contact

email: k.brohi@qmul.ac.uk

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    10.1016/j.jvs.2025.01.034
  • Brohi K (2025). The path to precision trauma care. Emergency Medicine Journal 42, (4) 220-221.
    10.1136/emermed-2025-214862
  • Davenport R, Brohi K, Aylwin C (). European Society for Vascular Surgery (ESVS) 2025 Clinical Practice Guidelines on the Management of Vascular Trauma. European Journal of Vascular and Endovascular Surgery .
    10.1016/j.ejvs.2024.12.018
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    10.3310/jytr6938
  • Alruqi F, Cole E, Brohi K (2024). Timings of Pre-hospital Life-saving Interventions During Mass Casualty Incidents: An Observational Simulation Pilot Study. Disaster Medicine and Public Health Preparedness 18e146-.
    10.1017/dmp.2024.201
  • Lendrum RA, Perkins Z, Marsden M et al. (2024). Prehospital Partial Resuscitative Endovascular Balloon Occlusion of the Aorta for Exsanguinating Subdiaphragmatic Hemorrhage. JAMA Surgery 159, (9) 998-1007.
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  • Maier CL, Brohi K, Curry N et al. (2024). Correction: Contemporary management of major haemorrhage in critical care. Intensive Care Medicine 50, (3) 490-490.
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  • Maier CL, Brohi K, Curry N et al. (2024). Contemporary management of major haemorrhage in critical care. Intensive Care Medicine 50, (3) 319-331.
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  • Van Gent J-M, Kaminski CW, Praestholm C et al. (2024). Empiric Cryoprecipitate Transfusion in Patients with Severe Hemorrhage: Results from the US Experience in the International CRYOSTAT-2 Trial. Journal of the American College of Surgeons 238, (4) 636-643.
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  • Schofield H, Lindsay C, Brohi K et al. (2024). Group B or not group B? An association between ABO, early mortality, and organ dysfunction in major trauma patients with shock. Journal of Thrombosis and Haemostasis 22, (3) 676-685.
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  • Rossetto A, Wohlgemut JM, Brohi K et al. (2023). Sonorheometry versus rotational thromboelastometry in trauma: a comparison of diagnostic and prognostic performance. Journal of Thrombosis and Haemostasis 21, (8) 2114-2125.
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  • Tucker H, Brohi K, Tan J et al. (). Association of red blood cells and plasma transfusion versus red blood cell transfusion only with survival for treatment of major traumatic hemorrhage in prehospital setting in England: a multicenter study. Critical Care 27, (1) 25-.
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  • Brohi K (2023). Shock, haemorrhage and transfusion. 11-23.
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  • Brohi K (2022). Foreword. Textbook of Acute Trauma Care vii-viii.
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  • Tallach R, Brohi K (2022). Embracing uncertainty in mass casualty incidents. British Journal of Anaesthesia 128, (2) e79-e82.
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  • Guerreiro ML, Brohi K (2020). Fibrino(Geno)Lysis: The New Kid in Town for Trauma Care. Journal of the American College of Surgeons 231, (4) s317-s318.
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  • (2020). FEATURED ARTICLES FOR CME CREDIT SEPTEMBER 2020. Journal of Trauma and Acute Care Surgery 89, (3) e89-e91.
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  • Spyropoulos AC, Brohi K, Caprini J et al. (2019). Scientific and Standardization Committee Communication: Guidance document on the periprocedural management of patients on chronic oral anticoagulant therapy: Recommendations for standardized reporting of procedural/surgical bleed risk and patient‐specific thromboembolic risk. Journal of Thrombosis and Haemostasis 17, (11) 1966-1972.
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  • Crewdson K, Rehn M, Brohi K et al. (2019). Response letter to Voelckel et al. Acta Anaesthesiologica Scandinavica 63, (1) 140-140.
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  • Crewdson K, Rehn M, Brohi K et al. (2019). Response to Burns et al. Acta Anaesthesiologica Scandinavica 63, (1) 138-138.
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  • Glasgow SM, Perkins ZB, Tai NRM et al. (2018). Development of a discrete event simulation model for evaluating strategies of red blood cell provision following mass casualty events. European Journal of Operational Research 270, (1) 362-374.
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  • PROWLE JR (2018). Acute Kidney Injury in Trauma Patients Admitted to Critical Care: Development and Validation of a Diagnostic Prediction Model. Scientific Reports .
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  • Crewdson K, Rehn M, Brohi K et al. (2018). Pre‐hospital emergency anaesthesia in awake hypotensive trauma patients: beneficial or detrimental?. Acta Anaesthesiologica Scandinavica 62, (4) 504-514.
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  • Brohi K, Dhadly P, Mauger J (1999). LETTERS TO THE EDITOR. Journal of Trauma and Acute Care Surgery 46, (4) 745.-.
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  • Ravalia A, Brohi K (1995). Fractured neck of femur in a patient with a complicated medical condition. British Journal of Hospital Medicine 53, (11) 588-.

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