Colonel Nigel Tai CBE

Honorary Professor of Trauma Surgery & Innovation

I am a consultant trauma and vascular surgeon at Barts Health NHS Trust, and UK Defence Medical Service 

I am a British Army surgeon who has worked at the Royal London Hospital as a consultant Trauma and Vascular Surgeon since 2006. I’ve been fortunate to lead high performing teams with Defence Medical Services and in Barts Health NHS Trust, and have used  experiences in both settings to inform my research interests. These include the management of major haemorrhage, decision-making, and the use of AI technology to support trauma clinicians. I lead the NHS Major Trauma Training Interface Group Fellowship programme and am a Reader in Military Surgery and Trauma in the department of Research and Clinical Innovation at HQ Defence Medical Services.



Selected Publications in Scientific Literature:

Identification of major hemorrhage in trauma patients in the prehospital setting: diagnostic accuracy and impact on outcome. Wohlgemut JM, Pisirir E, Stoner RS, Kyimi E, Christian M, Hurst T, Marsh W, Perkins ZB, Tai NRM. Trauma Surgery & Acute Care Open 2024;9: e001214. doi: 10.1136/tsaco-2023-001214.

Updating and recalibrating causal probabilistic models on a new target population. Kyrimi E, Stoner RS, Perkins ZB, Pisirir E, Wohlgemut JM, Marsh W, Tai NRM. J Biomed Inform. 2023 Dec 9;149: 104572. doi: 10.1016/j.jbi.2023.104572.

Emergency department Resuscitative Endovascular Balloon Occlusion of the Aorta in trauma patients with exsanguinating hemorrhage: The UK-REBOA randomized clinical trial. Jansen JO, Hudson J, Cochran C, MacLennan G, Lendrum R, Sadek S, Gillies K, Cotton S, Kennedy C, Boyers D, Ferry G, Lawrie L, Nath M, Wileman S, Forrest M, Brohi K, Harris T, Lecky F, Moran C, Morrison JJ, Norrie J, Paterson A, Tai N, Welch N, Campbell MK; UK-REBOA Study Group; Aylwin C, Bew D, Brooks A, Chinery J, Cowlam T, Frith D, George A, Hudson A, Johnstone P, Mahmood A, Novak A, O'Meara M, Reid S, Sattout A, Smith C, Stansfield T, Thompson J. JAMA. 2023 Nov 21;330(19):1862-1871. doi: 10.1001/jama.2023.20850. PMID: 37824132.

Enhancing the clinical relevance of haemorrhage prediction models in trauma (Letter). Tandle S, Wohlgemut JM, Marsden MER, Pisirir E, Kyrimi E, Stoner RS, Marsh W, Perkins ZB, Tai NRM. Mil Med Res. 2023 Sep 20;10(1):43. doi: 10.1186/s40779-023-00476-6. PMID: 37726859.

Understanding pre-hospital blood transfusion decision-making for injured patients: an interview study. Marsden MER, Kellett S, Bagga R, Wohlgemut JM, Lyon RL, Perkins ZB, Gillies K, Tai NR. Emerg Med J. 2023 Nov;40(11):777-784. doi: 10.1136/emermed-2023-213086. Epub 2023 Sep 13. PMID: 37704359.

Methods used to evaluate usability of mobile clinical decision support systems for healthcare emergencies: a systematic review and qualitative synthesis. Wohlgemut JM, Pisirir E, Kyrimi E, Stoner RS, Marsh W, Perkins ZB, Tai NRM. JAMIA Open. 2023 Jul 12;6(3):ooad051. doi: 10.1093/jamiaopen/ooad051. eCollection 2023 Oct. PMID: 37449057.

Diagnostic accuracy of clinical examination to identify life- and limb-threatening injuries in trauma patients. Wohlgemut JM, Marsden MER, Stoner RS, Pisirir E, Kyrimi E, Grier G, Christian M, Hurst T, Marsh W, Tai NRM, Perkins ZB. Scand J Trauma Resusc Emerg Med. 2023 Apr 7;31(1):18. doi: 10.1186/s13049-023-01083-z.

Causes and associations with mortality in patients with pelvic ring injuries with haemorrhagic shock. Walters S, Cuthbert R, Ward J, Arshad H, Culpan P, Perkins Z, Tai N, Bates P. Eur J Orthop Surg Traumatol. 2023 Oct;33(7):2971-2979. doi: 10.1007/s00590-023-03516-y. Epub 2023 Mar 16. PMID: 36922411.

Impact of ischemia duration on lower limb salvage in combat casualties. Perkins ZB, Kersey AJ, White JM, Lauria AL, Propper BW, Tai NRM, Rasmussen TE. Ann Surg. 2022 Sep 1;276(3):532-538. doi: 10.1097/SLA.0000000000005560.

Skill decay in surgeons deployed on military operations: a systematic review. Stansfield T, Tai N. BMJ Mil Health. 2022 May 19:e001919. doi: 10.1136/bmjmilitary-2021-001919.

The effectiveness and cost-effectiveness of resuscitative endovascular balloon occlusion of the aorta (REBOA) for trauma patients with uncontrolled torso haemorrhage: study protocol for a randomised clinical trial (the UK-REBOA trial). Jansen JO, Cochran C, Boyers D, Gillies K, Lendrum R, Sadek S, Lecky F, MacLennan G, Campbell MK; UK-REBOA Trial grantholders. Trials. 2022 May 12;23(1):384. doi: 10.1186/s13063-022-06346-1.

The outcome of a prediction algorithm should be a true patient state rather than an available surrogate (Letter).  Wohlgemut JM, Kyrimi E, Stoner RS, Pisirir E, Marsh W, Perkins ZB, Tai NRM. J Vasc Surg. 2022 Apr;75(4):1495-1496.

Defence Medical Services REBOA training course. Marsden MER, Park C, Barratt J, Tai N, Rees P. BMJ Mil Health 2021 Oct doi: 10.1136/bmjmilitary-2021-001926.

Surgical skill decay in the contingency era. Stansfield T, Tai N.  BMJ Mil Health. 2021 Oct;167(5):300-301. doi: 10.1136/bmjmilitary-2021-001921.

The DMS must rapidly reshape its systems to cultivate and sustain innovation and the implementation of new digital technologies. Buckley A, Tai N. BMJ Mil Health. 2021 Sep 22:bmjmilitary-2021-001924. doi: 10.1136/bmjmilitary-2021-001924.

Balloons on the battlefield: REBOA implementation in the UK Defence Medical Services. Marsden MER, Buckley AM, Park C, Tai N, Rees P. BMJ Mil Health. 2021 Aug 18:bmjmilitary-2021-001925. doi: 10.1136/bmjmilitary-2021-001925.

Remote ultrasound diagnostics disrupting traditional military frontline healthcare delivery. Blenkinsop G, Heller RA, Carter NJ, Burkett A, Ballard M, Tai N. BMJ Mil Health. 2021 Aug 9:bmjmilitary-2021-001821. doi: 10.1136/bmjmilitary-2021-001821.

Trauma Laparotomy in the UK: A Prospective National Service Evaluation. Marsden MER, Vulliamy PED, Carden R, Naumann DN, Davenport RA; National Trauma Research and Innovation Collaborative (NaTRIC). J Am Coll Surg. 2021 Sep;233(3):383-394.e1. doi: 10.1016/j.jamcollsurg.2021.04.031. Epub 2021 May 17. PMID: 34015456.

Pharmacokinetics of intramuscular tranexamic acid in bleeding trauma patients: a clinical trial. Grassin-Delyle S, Shakur-Still H, Picetti R, Frimley L, Jarman H, Davenport R, McGuinness W, Moss P, Pott J, Tai N, Lamy E, Urien S, Prowse D, Thayne A, Gilliam C, Pynn H, Roberts I. Br J Anaesth. 2021 Jan;126(1):201-209. doi: 10.1016/j.bja.2020.07.058. Epub 2020 Sep 30. PMID: 33010927.

Predicting the Outcome of Limb Revascularization in Patients With Lower-extremity Arterial Trauma: Development and External Validation of a Supervised Machine-learning Algorithm to Support Surgical Decisions. Perkins ZB, Yet B, Sharrock A, Rickard R, Marsh W, Rasmussen TE, Tai NRM. Ann Surg. 2020 Oct;272(4):564-572. doi: 10.1097/SLA.0000000000004132.

An incremental explanation of inference in Bayesian networks for increasing model trustworthiness and supporting clinical decision making. Kyrimi E, Mossadegh S, Tai N, Marsh W. Artif Intell Med. 2020 Mar;103:101812. doi: 10.1016/j.artmed. 2020.101812. Epub 2020 Jan 31.PMID: 32143808.

Early identification of Trauma-induced Coagulopathy: development and validation of a multivariable risk prediction model. Perkins ZB, Yet B, Marsden M, Glasgow S, Marsh W, Davenport R, Brohi K, Tai NRM. Ann Surg. 2020 Jan 14.

Trends in admission timing and mechanism of injury can be used to improve general surgical trauma training. Pearce AP, Marsden M, Newell N, Hancorn K, Lecky F, Brohi K, Tai N. Ann R Coll Surg Engl. 2020 Jan;102:36-42.

The feasibility of UK Trauma Training: the trauma TIG. Hancorn K, Daveport R, Griffiths M, Brooks A, Tai N. Bull R Coll Surg Engl. 2020 102(S1) e15-e18.

A Decade of Damage Control Resuscitation: New Transfusion Practice, New Survivors, New Directions. Cole E, Weaver A, Gall L, West A, Nevin D, Tallach R, O'Neill B, Lahiri S, Allard S, Tai N, Davenport R, Green L, Brohi K. Ann Surg. 2019 Oct 22.

Prehospital tranexamic acid shortens the interval to administration by half in Major Trauma Networks: a service evaluation. Marsden MER, Rossetto A, Duffield CAB, Woolley TGD, Buxton WP, Steynberg S, Bagga R, Tai NRM. Emerg Med J. 2019;36(7):395-400.

Management and outcome of 597 wartime penetrating lower extremity arterial injuries from an international military cohort. Sharrock AE, Tai N, Perkins Z, White JM, Remick KN, Rickard RF, Rasmussen TE. J Vasc Surg. 2019 Jul;70:224-232.

Development of a major incident triage tool: the importance of evidence from implementation studies (Letter). Marsden MER, Mossadegh S, Marsh W, Tai N. J R Army Med Corps. 2018 Sep 26

Paediatric blast injury: challenges and priorities. Bull A, Mayhew E, Reavley P, Tai N, Taylor S. Lancet Child Adolesc Health. 2018;2:310-311.

Outcomes following trauma laparotomy for hypotensive trauma patients: A UK military and civilian perspective. Marsden M, Carden R, Navaratne L, Smith IM, Penn-Barwell JG, Kraven LM, Brohi K, Tai NRM, Bowley DM. J Trauma Acute Care Surg. 2018 Sep;85(3):620-625.

Development of a discrete event simulation model for evaluating strategies of red blood cell provision following mass casualty events. Glasgow SM, Perkins ZB, Tai NRM, Brohi K, Vasilakis C. European Journal of Operational Research. 2018. 270 (1), 362-374.

Long-term, patient-centered outcomes of lower-extremity vascular trauma. Perkins ZB, Yet B, Glasgow S, Marsh DWR, Tai NRM, Rasmussen TE. J Trauma Acute Care Surg. 2018 Jul;85(1S Suppl 2):S104-S111.

The modified 'Jo'burg' technique for securing intercostal chest drains. Ablett DJ, Navaratne L, Chua D, Streets CG, Tai NRM. J R Army Med Corps. 2017;163:319-323.

United Kingdom military surgical preparedness for contingency operations. Khan M, Streets C, Tai N, Rickard R. J Trauma Acute Care Surg. 2017; (1 Suppl 1):S142-S144

Clinical evidence framework for Bayesian Networks. Yet B, Perkins ZB, Tai NRM, Marsh DWR. Knowledge and Information Systems 2017; 50, 117-143

Survival prediction algorithms miss significant opportunities for improvement if used for case selection in trauma quality improvement programs. Heim C, Cole E, West A, Tai N, Brohi K. Injury. 2016; 47:1960-5.

Managing the surge in demand for blood following mass casualty events: Early automatic restocking may preserve red cell supply. Glasgow S, Vasilakis C, Perkins Z, Brundage S, Tai N, Brohi K. J Trauma Acute Care Surg. 2016;81:50-7.

Management and closure of the open abdomen after damage control laparotomy for trauma. A systematic review and meta-analysis Sharrock AE, Barker T, Yuen HM, Rickard R, Tai N. Injury. 2016; 47:296-306.

Consensus recommendations for essential vascular care in low-and middle-income countries. Stewart BT, Gyedu A, Giannou C, Mishra B,  Rich N, Wren SM, Mock C, Kushner AL, Alexander P, Amponsah-Manu F, Dardik A, Darko ND, Elster E, Harris MJ, Johnston L, Junkins S, Kokuro C, Kuwayama D, Labi-Addo W, Morna M, Oppong-Nketia V, Orgoi S, Quiroga E, Remick K, Tai N, Veller M, Yangi-Angate H. J Vascular Surg. 2016. 64:6; 1770-1779.

Surgeon preparedness for mass casualty events: adapting essential military surgical lessons for the home front. Remick KN, Shackelford S, Oh JS, Seery JM, Grabo D,  Chovanes J, Gross KR, Nessen SC, Tai NRM, Rickard RF, Elster E, Schwab CW. Am J Disaster Med 2016 ;11:77-87.

Meta-analysis of prognostic factors for amputation following surgical repair of lower extremity vascular trauma. Perkins ZB, Yet B, Glasgow S, Cole E, Marsh W, Brohi K, Rasmussen TE, Tai NR. Br J Surg. 2015; 102: 436-50.

A survey of major trauma centre staffing in England. Jansen JO, Morrison JJ, Tai NR, Midwinter MJ. J R Army Med Corps. 2015; 161:341-4.

Stenting for a stabbing. Ahmed U, Whitaker J, Gademsetty C, Tai N. BMJ 2015; 351: h5502.

Impact on outcome of a targeted performance improvement programme in haemodynamically unstable patients with a pelvic fracture. Perkins ZB, Maytham GD, Koers L, Bates P, Brohi K, Tai NR Bone Joint J 2014;96:1090-7.

Combining data and meta-analysis to build Bayesian Networks for clinical decision support. Yet B, Perkins ZB, Rasmussen TE. Tai NRM, Marsh DRW. J Biomed Informatics. 2014; 52: 373-385.

Not just data: a method for improving prediction with knowledge. Yet B, Perkins Z, Fenton N, Tai N, Marsh W. J Biomed Informatics. 2014; 48: 28-37.

Trauma Care at a multinational United Kingdom-led Role 3 combat hospital: resuscitation outcomes from a multidisciplinary approach. Tubbs CC, Oh JS, Do NV, Tai NR, Meissel MP, Place ML. Mil Medicine. 2014. 179: 1258-1262.

The Damage Control Set: rethinking for contingency. Tai N, Parker P. J R Army Med Corps 2013;159:314-5.

Injury pattern and mortality of noncompressible torso hemorrhage in UK combat casualties. Morrison JJ, Stannard A, Rasmussen TE, Jansen JO, Tai NR, Midwinter MJ. J Trauma Acute Care Surg. 2013;75: S263-8.

A comprehensive review of blood product use in civilian mass casualty events. Glasgow S, Davenport R, Perkins Z, Tai N, Brohi K. J Trauma Acute Care Surg. 2013 Sep;75:468-74.

Military treatment of splenic injury in the era of non-operative management. Mossadegh S, Midwinter M, Sapsford W, Tai N. J R Army Med Corps. 2013;159:110-3.

Opportunities for improvement in the management of patients who die from haemorrhage after trauma. O'Reilly D, Mahendran K, West A, Shirley P, Walsh M, Tai N. Br J Surg. 2013;100:749-55.

Venous thromboembolism in the trauma patient. Tai SMM, Buddhdev P, Baskaradas A, Sivarasan N, Tai NRM. Orthopaedics and Trauma. 2013;27: 379-392.

Frequency and relevance of acute peritraumatic pulmonary thrombus diagnosed by computed tomographic imaging in combat casualties. Lundy JB, Oh JS, Chung KK, Ritter JL, Gibb I, Nordmann GR, Sonka BJ, Tai NR, Aden JK, Rasmussen TE. J Trauma and Acute Care Surgery 2013;75: S215-S220.

Improvised explosive device-related pelvi-perineal trauma: UK military experience, literature review and lessons for civilian trauma teams. Mossadegh S, Tai N, Midwinter M, Parker P. Bull R Coll Surg Eng. 2013;95:1-5.

Planning trauma care services in the UK: surgical workforce development remains a challenge. Jansen JO, Tai NR, Midwinter MJ. BMJ. 2013 Feb 11;346:f738.

Systematic review and meta-analysis of open surgical and endovascular management of thoracic outlet vascular injuries. Sinha S, Patterson BO, Ma J, Holt PJ, Thompson MM, Carell T, Tai N, Loosemore TM, London Trauma Network. J Vasc Surgery 2013;57: 547-567.

Epidemiology and Outcome of Vascular Trauma at a British Major Trauma Centre. Perkins ZB, De'ath HD, Aylwin C, Brohi K, Walsh M, Tai NR. Eur J Vasc Endovasc Surg. 2012 Jun 1.

Preparing the surgeon for war: present practices of US, UK and Canadian militaries and future directions for the US military. DuBose J, Rodriguez C, Martin M, Nunez T, Dorlac W, King D, Schreiber M, Vercruysse G, Tien, H, Brooks A, Tai N, Midwinter M, Easteidge B, Holcomb J, Pruitt B. J Trauma Acute Care Surgery. 2012;73: S423-S430

Commentary: the use of Celox Gauze as an adjunct to pelvic packing in otherwise uncontrollable pelvic haemorrhage secondary to penetrating trauma. Tai N. J R Army Med Corps 2012;4:333-334.

Improvised explosive device related pelvi-perineal trauma: anatomic injuries and surgical management. Mossadegh S, Tai N, Midwinter M, Parker P. J Trauma Acute Care Surg 2012; 73: S24-31.

Early management of proximal traumatic lower extremity amputation and pelvic injury caused by improvised explosive devices (IEDs). Jansen JO, Thomas GOR, Adams SA, Tai NRM, Russell R, Morrison J, Clasper J, Midwinter M. Injury 2012;43:976-979.

Imaging vascular trauma. Patterson BO, Holt PJ, Cleanthis M, Tai N, Loosemore T. Br J Surg. 2012;99:494-505.

Factors affecting outcome after traumatic limb amputation. Perkins ZB, De'Ath HD, Sharp G, Tai NR. Br J Surg. 2012 ;99:1:75-86.

Major trauma and urban cyclists: physiological status and injury profile. Manson J, Cooper S, West A, Foster E, Cole E, Tai NR. Emerg Med J. 2012

Difficult decisions in the surgical care of military casualties with major torso trauma. Bowley DM, Jansen JO, Nott D, Sapsford W, Streets CG, Tai NR. J R Army Med Corps. 2011;157: S324-33.

Management of intestinal injury in deployed UK hospitals. Fries CA, Penn-Barwell J, Tai NRM, Hodgetts TJ, Midwinter MJ, Bowley DM. BMJ Military Health. 2011;157;370-373.

Right turn resuscitation: frequently asked questions. Tai NR, Russell R. J R Army Med Corps. 2011;157: S310-4.

Vascular injury in the United Kingdom. Stannard A, Bohi K, Tai N. Perspectives Vasc Surg Endovasc Therapy. 2011;1:27-33.

Extremity compartment syndrome with Sickle Cell Trait. Newton N, Davenport R, Tai NR. J R Army Med Corps 2011;157:418.

Deaths from trauma in London -a single centre experience. Chalkley D, Cheung G, Walsh M, Tai N. Emerg Med J. 2011;28:305-9.

Outcome after vascular trauma in a deployed military trauma system. Stannard A, Brown K, Benson C, Clasper J, Midwinter M, Tai NR. Brit J Surg 2011 ;98:228-34.

The UK’s NHS trauma systems: lessons from military experience. Hettiaratchy S, Tai N, Mahoney P, Hodgetts T. Lancet. 2010;376: 149-51.

A major trauma centre is a specialty hospital not a hospital of specialties. RA Davenport, N Tai, A West, O Bouamra, C Aylwin, M Woodford, A McGinley, F Lecky, MS Walsh, K Brohi. Brit J Surg 2010;97:109-117.

Civilian trauma care and the defence medical services- a prospectus for partnership? Tai N. J R Army Med Corps 2009;155:246-7.

Military junctional trauma. Tai NR, Dickson EJ. J R Army Med Corps 2009;155:285-92.

Optimal clinical timelines- a consensus from the academic department of military surgery and trauma. Tai NR, Brooks A, Midwinter M, Clasper JC, Parker PJ. J R Army Med Corps 2009;155:253-6.

Traumatic amputation – a contemporary approach. A Healey, N Tai.  Trauma 2009; 11: 177-187.

Military junctional trauma. Tai N, Dickson EJ. BMJ Military Health 2009;155: 285-292.

An analysis of in-hospital deaths at a modern combat support hospital. M Martin, J Oh, H Currier, N Tai, A Beekley, M Eckert, J Holcomb. Journal of Trauma 2009; 66:S1-60.

Complications of extremity vascular injuries in conflict. Brown K, Ramasamy A, Tai N, Macleod J, Midwinter M, Clasper JC. J Trauma Acute Care Surgery. 2009;66: S145-149.

Forward trauma surgery in Afghanistan: lessons learnt on the modern asymmetric battlefield. N Tai, P Hill, A Kay, P Parker. JR Army Medical Corps 2008: 154;14-18.

Key performance indicators in British military trauma. Stannard A, Tai NR, Bowley DM, Midwinter M, Hodgetts TJ. World J Surg 2008; 32:1870-3.

Field trauma care in the 21st century. O Reilly D, Konig T, Tai N. 2008; BMJ Military Health; 154: 257-264.

Operational mortality of UK service personnel in Iraq and Afghanistan: a one year analysis 2006-2007. Hodgetts T, Davies S, Midwinter M, Russell R, Smith J, Clasper J, Tai N, Lewis E, Ollerton J, Massetti P, Moorhouse I, Hunt N, Hepper A. JR Army Med Corps 2009; 153:252-254.

Single-centre experience of endovascular  abdominal aortic aneurysm repair (EVAR) in patients not participating in the UK EVAR trials. Sajid MS, Tai NRM, Iftikhar M, Platts A, Baker DM, Hamilton G. Vasc and Endovasc Surgery. 2007; 41:383-388.

Anterior spinal artery syndrome after abdominal stabbing and resuscitative thoracotomy. Aylwin C, Tai N, Walsh M. J Trauma Acute Care Surgery 2007;62: 526-528.

The neglect of trauma surgery. Tai NRM, Ryan JM, Brooks AJ. BMJ 2006; 332: 805 – 806.

Knee versus thigh length graduated compression stockings for prevention of deep venous thrombosis: a systematic review. Sajid MS, Tai NRM, Goli G, Baker DM, Hamilton G. Eur J Vasc Endovasc Surg. 2006;32:730-736.

A theme issue by, for, and about Africa: South Africa is still blighted by trauma. Bowley DM, Dickson EJ, Tai N, Goosen J, Boffard KD. BMJ. 2005 Oct 1;331

Host should also protect students on electives from HIV. Tai NR, Nielson S, Boffard K. BMJ. 2003 Feb 8;326.

An assessment of covalent grafting of RGD peptides to the surface of a compliant poly(carbonate-urea)urethane vascular conduit versus conventional biological coatings: its role in enhancing cellular retention. Krijgsman B, Seifalian AM, Salacinski HJ, Tai NR, Punshon G, Fuller BJ, Hamilton G. Tissue Eng. 2002;8:673-80.

In vitro stability of a novel compliant poly(carbonate-urea) urethane to oxidative and hydrolytic stress. Salacinski HJ, Tai NR, Carson RJ, Edwards A, Hamilton G, Seifalian AM. J Biomed Mater Res. 2002;59:207-18.

Optimal endothelialisation of a new compliant poly(carbonate-urea)urethane vascular graft with effect of physiological shear stress. Salacinski HJ, Tai NR, Punshon G, Giudiceandrea A, Hamilton G, Seifalian AM. Eur J Vasc Endovasc Surg. 2000;20:342-52.

In vivo femoropopliteal arterial wall compliance in subjects with and without lower limb vascular disease. Tai NR, Giudiceandrea A, Salacinski HJ, Seifalian AM, Hamilton G. J Vasc Surg. 1999;30:936-45.

Modern management of pulmonary embolism. Tai NR, Atwal AS, Hamilton G. Br J Surg. 1999 Jul;86(7):853-68.

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