Dr Paul Vulliamy
I am a Senior Clinical Lecturer in Trauma Sciences at the Blizard Institute and Honorary Consultant Trauma Surgeon at the Royal London Hospital. I first joined C4TS as a clinical research fellow and completed my PhD in 2019 under the supervision of Professor Karim Brohi and Professor Tim Warner. I then took up a post as Clinical Lecturer in trauma sciences and Specialist Registrar in general surgery. After completing my higher surgical training and subspecialty training in trauma, I was appointed to my current position where my time is split between clinical and academic commitments.
My primary research focus is on the role of platelets in the pathophysiology of acute traumatic coagulopathy and post-injury organ dysfunction. I have a particular interest in the immunomodulatory roles of platelets, the mechanisms of damage sensing by platelets, and the behaviour of transfused platelets during major haemorrhage.
In addition to my research activities, I co-ordinate medical student placements within the group and I contribute to the Haemorrhage and Coagulopathy module of the Trauma Sciences MSc. I am also co-principal investigator of the ACITII study, our platform observational study, and a founding member of the National trauma research and innovation collaborative (NaTRIC). I participate regularly in our public engagement activities, and run outreach events through the Blizard Institute which support young people from the local community to get involved in scientific and clinical careers. I also have a keen interest in medical art, and was previously awarded the life Sciences Image Award for my work entitled ‘White Blood Cells in Colour’.
Contact
email: p.vulliamy@qmul.ac.uk
- Rossetto A, Armstrong PC, Allan HE et al. (2026). Differential benefits of cold-stored and room temperature platelets in bleeding trauma patients. Journal of Thrombosis and Haemostasis 24, (4) 1559-1563.
10.1016/j.jtha.2025.11.037 - Edmiston T, Bath MF, Caceres E et al. (2025). Variation in global trauma care: a survey of 187 hospitals across 51 countries. BMJ Global Health 10, (11) e021784-.
10.1136/bmjgh-2025-021784 - Rossetto A, Reynolds J, Ykema E et al. (2025). Postresuscitation platelet transfusion in major trauma patients. Transfusion 65, (11) 2055-2064.
10.1111/trf.18414 - Bath MF, Amoako J, Kohler K et al. (2025). Global variation in patient factors, interventions, and postoperative outcomes for those undergoing trauma laparotomy: an international, prospective, observational cohort study. The Lancet Global Health 13, (11) e1837-e1848.
10.1016/s2214-109x(25)00303-1 - Hurndall K-H, Leatherby R, Waton S et al. (2026). The Vascular Interventions and Surgery in Trauma Audit (VISTA): A Prospective National Service Evaluation of Vascular Trauma in the UK. European Journal of Vascular and Endovascular Surgery 71, (3) 455-462.
10.1016/j.ejvs.2025.08.040 - Omori K, Vulliamy P, Aylwin C et al. (). Comparative analysis of emergency medical systems in the UK and Japan: recommendations for Japan based on on-site observations in the UK. International Journal of Emergency Medicine 18, (1) 155-.
10.1186/s12245-025-00956-7 - Allan HE, Dark N, Vulliamy P et al. (2025). Platelet mitochondrial transfer via extracellular vesicles modulates neutrophil phenotype and function. Journal of Thrombosis and Haemostasis 23, (11) 3665-3677.
10.1016/j.jtha.2025.08.004 - Rossetto A, Kerner S, Ykema E et al. (2025). Thrombocytopenia in critically ill trauma patients is associated with the pattern and duration of postinjury organ dysfunction. Research and Practice in Thrombosis and Haemostasis 9, (4) 102890-.
10.1016/j.rpth.2025.102890 - Rossetto A, Vulliamy P, Huish S et al. (2025). Comparison of whole blood versus red blood cells and plasma to correct trauma‐induced coagulopathy ex vivo. Transfusion 65, (3) 624-636.
10.1111/trf.18143 - Bradley RA, Baker E, Caponi N et al. (2025). Management and outcomes of rib fractures in the UK: a national service evaluation. Journal of Surgical Protocols and Research Methodologies 2025snaf001-.
10.1093/jsprm/snaf001 - Murphy S, Jeffery H, Vulliamy P et al. (2024). 174 The Histopathological Assessment of Gastro-Oesophageal Carcinoma Resection Specimens: A Quality Improvement project. British Journal of Surgery 111, (Supplement_6) znae163.489-.
10.1093/bjs/znae163.489 - Bravo L, Simões JF, Cardoso VR et al. (2024). A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts. The Lancet Digital Health 6, (7) e507-e519.
10.1016/s2589-7500(24)00065-7 - Shepherd JM, Vulliamy P, Marsden MER (2024). ASGBI trauma committee position statement: a national audit of trauma laparotomy in the UK – an unmet need. British Journal of Anaesthesia 132, (5) 849-850.
10.1016/j.bja.2024.03.001 - Vulliamy P (2024). Platelets in Hemostasis, Thrombosis, and Inflammation After Major Trauma. Arteriosclerosis Thrombosis and Vascular Biology 44, (3) 545-557.
10.1161/atvbaha.123.318801 - Foley MP, Walsh SR, Doolan N et al. (2024). Sensitivity Analysis Does Not Alter Conclusions. European Journal of Vascular and Endovascular Surgery 67, (3) 520-522.
10.1016/j.ejvs.2023.12.007 - Schofield H, Rossetto A, Armstrong PC et al. (2024). Immature platelet dynamics are associated with clinical outcomes after major trauma. Journal of Thrombosis and Haemostasis 22, (4) 926-935.
10.1016/j.jtha.2023.12.002 - Gunn F, Stevenson R, Almuwallad A et al. (2024). A comparative analysis of tranexamic acid dosing strategies in traumatic major hemorrhage. Journal of Trauma and Acute Care Surgery 96, (2) 216-224.
10.1097/ta.0000000000004177 - Foley MP, Walsh SR, Doolan N et al. (2023). Systematic Review and Meta-Analysis of Lower Extremity Vascular Complications after Arterial Access for Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA): An Inevitable Concern?. Journal of Vascular Surgery 78, (3) 838-.
10.1016/j.jvs.2023.06.018 - Schofield H, Rossetto A, Armstrong PC et al. (). Immature platelet dynamics are associated with clinical outcomes after major trauma. 2023.08.25.23294628-.
10.1101/2023.08.25.23294628 - Rossetto A, Torres T, Platton S et al. (2023). A new global fibrinolysis capacity assay for the sensitive detection of hyperfibrinolysis and hypofibrinogenemia in trauma patients. Journal of Thrombosis and Haemostasis 21, (10) 2759-2770.
10.1016/j.jtha.2023.05.005 - Foley MP, Walsh SR, Doolan N et al. (2023). Editor's Choice – Systematic Review and Meta-Analysis of Lower Extremity Vascular Complications after Arterial Access for Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA): An Inevitable Concern?. European Journal of Vascular and Endovascular Surgery 66, (1) 103-118.
10.1016/j.ejvs.2023.02.007 - Tucker H, Ramage L, Greenhalgh R et al. (2022). Trauma emergency thoracotomy for resuscitation in shock—a multi-centre evaluation of current UK practice of pre-hospital and emergency department resuscitative thoracotomy in trauma. Journal of Surgical Protocols and Research Methodologies 2022, (3) snac011-.
10.1093/jsprm/snac011 - Moffatt S, Vulliamy P (2023). Does pre-injury clopidogrel use increase the risk of intracranial haemorrhage post head injury in adult patients? A systematic review and meta-analysis. Emergency Medicine Journal 40, (3) 175-181.
10.1136/emermed-2021-212225 - Vulliamy P, Hancorn K, Glasgow S et al. (). Age-related injury patterns resulting from knife violence in an urban population. Scientific Reports 12, (1) 15250-.
10.1038/s41598-022-17768-x - Fotopoulou C, Khan T, Bracinik J et al. (2022). Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study. American Journal of Obstetrics and Gynecology 227, (5) 735.e1-735.e25.
10.1016/j.ajog.2022.06.052 - Sloos PH, Vulliamy P, van 't Veer C et al. (2022). Platelet dysfunction after trauma: From mechanisms to targeted treatment. Transfusion 62, (Suppl 1) s281-s300.
10.1111/trf.16971 - Abdeen B, Vulliamy P, English W et al. (2021). P-BN06 Percutaneous cholecystostomy rates are increased following COVID-19 induced disruption to elective surgical pathways. British Journal of Surgery 108, (Supplement_9) znab430.008-.
10.1093/bjs/znab430.008 - Pati-Alam A, Mukherjee D, Mukherjee S (2021). P-EGS21 The impact of COVID-19 on operative difficulty and outcomes of laparoscopic cholecystectomy. British Journal of Surgery 108, (Supplement_9) znab430.081-.
10.1093/bjs/znab430.081 - Thomas JJ, Mitra S, Vulliamy P (2021). P-P52 Overuse of CT scans in the diagnosis of Acute Pancreatitis. British Journal of Surgery 108, (Supplement_9) znab430.274-.
10.1093/bjs/znab430.274 - Abdeen B, Vulliamy P, English W et al. (2021). PWE-20 Percutaneous cholecystostomy rates are increased following COVID-19 induced disruption to elective surgical pathways. Gut 70, (Suppl 4) a113-a113.
10.1136/gutjnl-2021-bsg.210 - Rossetto A, Vulliamy P, Lee KM et al. (2022). Temporal Transitions in Fibrinolysis after Trauma: Adverse Outcome Is Principally Related to Late Hypofibrinolysis. Anesthesiology 136, (1) 148-161.
10.1097/aln.0000000000004036 - Bedwani NH, English W, Singh S et al. (2021). EP.WE.573Outcomes of Emergency Laparotomies during the COVID-19 Pandemic - A retrospective cohort study. British Journal of Surgery 108, (Supplement_7) znab308.069-.
10.1093/bjs/znab308.069 - Vulliamy P, Marsden M, Carden R et al. (2021). SP9.1.7 Emergency Laparotomy for Trauma in the United Kingdom and Ireland: a Prospective Multicentre Study. British Journal of Surgery 108, (Supplement_7) znab361.170-.
10.1093/bjs/znab361.170 - Glasbey J, Ademuyiwa A, Adisa A et al. (2021). Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study. The Lancet Oncology 22, (11) 1507-1517.
10.1016/s1470-2045(21)00493-9 - Marsden MER, Vulliamy PED, Carden R et al. (2021). Trauma Laparotomy in the UK: A Prospective National Service Evaluation. Journal of the American College of Surgeons 233, (3) 383-394.e1.
10.1016/j.jamcollsurg.2021.04.031 - Smith C, Singh S, Vulliamy P (2021). Bouveret syndrome: a rare cause of gastric outlet obstruction. BMJ Case Reports 14, (4) e240236-.
10.1136/bcr-2020-240236 - Bedwani NH, English W, Smith C et al. (2021). Outcomes of Emergency Laparotomies during the COVID-19 Pandemic - A retrospective cohort study. BRITISH JOURNAL OF SURGERY 108.
- Thomas JJ, Mitra S, Osilli D et al. (2021). Overuse of CT scans in the diagnosis of Acute Pancreatitis. BRITISH JOURNAL OF SURGERY 108.
- Abdeen B, Vulliamy P, English W et al. (2021). Percutaneous cholecystostomy rates are increased following COVID-19 induced disruption to elective surgical pathways. BRITISH JOURNAL OF SURGERY 108.
- Pati-Alam A, Vulliamy P, Mukherjee D (2021). The impact of COVID-19 on operative difficulty and outcomes of laparoscopic cholecystectomy. BRITISH JOURNAL OF SURGERY 108.
- Baksaas-Aasen K, Gall LS, Stensballe J et al. (2021). Viscoelastic haemostatic assay augmented protocols for major trauma haemorrhage (ITACTIC): a randomized, controlled trial. Intensive Care Medicine 47, (1) 49-59.
10.1007/s00134-020-06266-1 - English W, Vulliamy P, Banerjee S (2020). Surgical training during the COVID-19 pandemic – the cloud with a silver lining?. British Journal of Surgery 107, (9) e343-e344.
10.1002/bjs.11801 - Vulliamy P, Montague SJ, Gillespie S et al. (2020). Loss of GPVI and GPIbα contributes to trauma-induced platelet dysfunction in severely injured patients. Blood Advances 4, (12) 2623-2630.
10.1182/bloodadvances.2020001776 - Nepogodiev D, Bhangu A, Glasbey JC et al. (2020). Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study. The Lancet 396, (10243) 27-38.
10.1016/s0140-6736(20)31182-x - Vulliamy P, Jacob S, Davenport RA (2020). Acute aorto‐iliac and mesenteric arterial thromboses as presenting features of COVID‐19. British Journal of Haematology 189, (6) 1053-1054.
10.1111/bjh.16760 - Gall LS, Vulliamy P, Brohi K et al. (2020). Response to the Comment on "The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients". Annals of Surgery 271, (4) e111-e112.
10.1097/sla.0000000000003691 - Cole E, Gillespie S, Vulliamy P et al. (2020). Multiple organ dysfunction after trauma. British Journal of Surgery 107, (4) 402-412.
10.1002/bjs.11361 - Vulliamy P, Kornblith LZ, Kutcher ME et al. (2021). Alterations in platelet behavior after major trauma: adaptive or maladaptive?. Platelets 32, (3) 295-304.
10.1080/09537104.2020.1718633 - Sohrabi C, Gillespie S, Rossetto A et al. (2020). Circulating levels of platelet factor 4 are elevated in the acute phase after severe traumatic brain injury. BRITISH JOURNAL OF SURGERY 107128-128.
- Baksaas-Aasen K, Gall LS, Stensballe J et al. (2020). Viscoelastic Haemostatic Assay Augmented Protocols for Major Trauma Haemorrhage (ITACTIC): A Randomised, Controlled Trial. .
10.2139/ssrn.3523858 - Vulliamy P, Gillespie S, Armstrong PC et al. (2019). Histone H4 induces platelet ballooning and microparticle release during trauma hemorrhage. Proceedings of the National Academy of Sciences of the United States of America 116, (35) 17444-17449.
10.1073/pnas.1904978116 - Sordi R, Chiazza F, Collotta D et al. (2021). Resolvin D1 Attenuates the Organ Injury Associated With Experimental Hemorrhagic Shock. Annals of Surgery 273, (5) 1012-1021.
10.1097/sla.0000000000003407 - Gall LS, Vulliamy P, Gillespie S et al. (2019). The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients. Annals of Surgery Publish Ahead of Print, (&NA;) &na-.
10.1097/sla.0000000000002733 - Gall LS, Vulliamy P, Gillespie S et al. (2019). The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients. Ann Surg 269, (6) 1184-1191.
10.1097/SLA.0000000000002733 - Vulliamy P, Thaventhiran AJ, Davenport RA (2019). What's new for trauma haemorrhage management?. British Journal of Hospital Medicine 80, (5) 268-273.
10.12968/hmed.2019.80.5.268 - Vulliamy P, Faulkner M, Kirkwood G et al. (2018). Temporal and geographic patterns of stab injuries in young people: a retrospective cohort study from a UK major trauma centre. BMJ Open 8, (10) e023114-.
10.1136/bmjopen-2018-023114 - (2017). Late-Breaking Science Abstracts From the American Heart Association’s Scientific Sessions 2017 and Late-Breaking Abstracts in Resuscitation Science From the Resuscitation Science Symposium 2017. Circulation 136, (24) e448-e467.
10.1161/cir.0000000000000546 - Vulliamy P, Gillespie S, Gall LS et al. (2017). Platelet transfusions reduce fibrinolysis but do not restore platelet function during trauma hemorrhage. Journal of Trauma and Acute Care Surgery 83, (3) 388-397.
10.1097/ta.0000000000001520 - Thin N, Kim H, Ridgeon A et al. (2017). IS STRAIGHT-TO-TEST COLONOSCOPY A FEASIBLE STRATEGY IN ASSESSING 2 WEEK WAIT PATIENTS?: A PROSPECTIVE QUALITY IMPROVEMENT FEASIBILITY PILOT STUDY. DISEASES OF THE COLON & RECTUM 60, (6) E540-E541.
- Vulliamy P, Gillespie S, Armstrong PC et al. (2017). Platelets Shift Towards a Procoagulant and Proinflammatory Phenotype at the Expense of Aggregation During Trauma Hemorrhage: a Potential Role of Extracellular Histones. CIRCULATION 136, (24) E464-E464.
- Vulliamy P, McCluney S, Raouf S (2016). Trends in urgent referrals for suspected colorectal cancer: an increase in quantity, but not in quality. Annals of The Royal College of Surgeons of England 98, (8) 564-567.
10.1308/rcsann.2016.0273 - Manson J, Cole E, De’Ath HD et al. (2016). Early changes within the lymphocyte population are associated with the development of multiple organ dysfunction syndrome in trauma patients. Critical Care 20, (1) 176-.
10.1186/s13054-016-1341-2 - Vulliamy P, McCluney S, Mukherjee S (2016). Postoperative Elevation of the Neutrophil: Lymphocyte Ratio Predicts Complications Following Esophageal Resection. World Journal of Surgery 40, (6) 1397-1403.
10.1007/s00268-016-3427-z - Vulliamy P, McCluney S, Ashby L et al. (2016). Post-operative elevation of the neutrophil: lymphocyte ratio predicts complications following oesophageal resection. BRITISH JOURNAL OF SURGERY 10345-46.
- Pirmadjid N, Freeman A (2015). An audit of the accuracy of discharge information and clinical coding in surgical patients. International Journal of Surgery 23s69-.
10.1016/j.ijsu.2015.07.303 - Vulliamy PE, Perkins ZB, Brohi K et al. (2016). Persistent lymphopenia is an independent predictor of mortality in critically ill emergency general surgical patients. European Journal of Trauma and Emergency Surgery 42, (6) 755-760.
10.1007/s00068-015-0585-x - Abukar AA, Leung P, Vulliamy P (). An unusual cause of abdominal pain in a middle-aged man. BMJ Case Reports 2015bcr2015211986-.
10.1136/bcr-2015-211986 - Vulliamy P, McCluney S, Banerjee S (2015). PTH-318 Five-year trends in urgent referrals for suspected colorectal cancer – an increase in quantity but not in quality. Gut 64, (Suppl 1) a549-.
10.1136/gutjnl-2015-309861.1204 - Vulliamy P, Perkins Z (2015). Persistent lymphopenia is associated with increased mortality in critically ill emergency surgical patients. BRITISH JOURNAL OF SURGERY 10244-44.
- Vulliamy PE, Perkins ZB, Brohi K et al. (2015). SEVERE LYMPHOPENIA IN EMERGENCY SURGICAL PATIENTS IS ASSOCIATED WITH ILLNESS SEVERITY AND MORTALITY. SHOCK 4410-11.
- Vulliamy P (2013). Evaluation of a peer mentoring scheme in core surgical trainees. International Journal of Surgery 11, (8) 698-.
10.1016/j.ijsu.2013.06.593 - Vulliamy P, Hariharan V, Gutmann J (2013). Superior mesenteric artery syndrome and the 'nutcracker phenomenon'. BMJ Case Reports .
10.1136/bcr-2013-008734 - Vulliamy P (2013). Peer-mentoring junior surgical trainees in the United Kingdom: a pilot program. Medical Education Online 18, (1) 20825-.
10.3402/meo.v18i0.20825 - Vulliamy P, Hariharan V, Gutmann J et al. (). Superior mesenteric artery syndrome and the ‘nutcracker phenomenon’. BMJ Case Reports 2013bcr2013008734-.
10.1136/bcr-2013-008734 - Vulliamy P, Berner AM, Farooq MS (2013). Near-fatal small bowel ischaemia secondary to sacrocolpopexy mesh. BMJ Case Reports .
10.1136/bcr-2012-008179 - Vulliamy P, Berner AM, Farooq MS et al. (). Near-fatal small bowel ischaemia secondary to sacrocolpopexy mesh. BMJ Case Reports 2013bcr2012008179-.
10.1136/bcr-2012-008179 - Vulliamy P, Junaid I (2013). Peer-mentoring junior surgical trainees in the United Kingdom: a pilot program. Med Educ Online 18, (1) 20825-.
10.3402/meo.v18i0.20825 - Vulliamy P, Ivanov B, Izhar A et al. (2013). Positron Emission Tomography in the Initial Staging of Oesophageal and Junctional Malignancy - Who Does it Benefit?. BRITISH JOURNAL OF SURGERY 10036-36.
- Vulliamy P, Manson J, Brohi K (2013). The admission differential white cell count in trauma - relationship with shock, injury severity and outcome. BRITISH JOURNAL OF SURGERY 10030-30.
- Vulliamy PE, McCormack DJ, Szczeklik M et al. (2012). Coarctation repair mimicking acute aortic dissection. European Journal of Cardio-thoracic Surgery 42, (6) 1055-1055.
10.1093/ejcts/ezs336 - De’Ath HDI, Vulliamy PED (2012). A large ventricular septal defect complicating resuscitation after blunt trauma. Journal of Emergencies Trauma and Shock 5, (4) 350-352.
10.4103/0974-2700.102409 - Vulliamy PE, Lau K (2012). Minerva. British Medical Journal 344e2876-.
10.1136/bmj.e2876 - Vulliamy P, Srilekha A, Kyriakides C (2011). Operative repair of an incidentally diagnosed giant hepatic artery aneurysm. Journal of Surgical Case Reports 2011, (3) 1-1.
10.1093/jscr/2011.3.1 - Manson J, Davenport R, Coates A et al. (2011). Trauma: Characterising the cytokine response to tissue damage. BRITISH JOURNAL OF SURGERY 9822-22.
- Allan HE, Dark N, Vulliamy P et al. (). Platelet mitochondrial transfer via extracellular vesicles modulates neutrophil phenotype and function. .
10.1101/2025.01.29.635414 - Vulliamy P, Gall L, Brohi KARIM et al. (). Response to: Comment on The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients. Annals of Surgery .
10.1097/SLA.0000000000003691 - Rossetto A, Kerner S, Ykema E et al. (). Thrombocytopenia in critically ill trauma patients is associated with the pattern and duration of post-injury organ dysfunction. .
10.1101/2025.03.04.25323139
