Dr Zane Perkins

Honorary Senior Lecturer

I am a consultant Trauma & General (Upper Gastrointestinal) surgeon at the Royal London Hospital and a consultant in prehospital care with London’s Air Ambulance. I studied medicine at the University of the Witwatersrand in Johannesburg, South Africa, where my keen interest in the care of the critically injured developed. Since then, I have trained in busy trauma systems in Johannesburg, Durban, and London. I completed UK higher surgical training in the Kent, Surrey, and Sussex Deanery and am a Fellow of the Royal College of Surgeons of England.

Research:

I am an honorary senior lecturer in Trauma Science at the Blizard Institute, and an Academic Fellow at the Digital Environment Research Institute (DERI) at Queen Mary University of London. I joined the Centre for Trauma Sciences as a Clinical Research Fellow and was awarded a Ph.D. in 2016 for my work on Bayesian Network powered predictive analytics to support clinical decision-making in trauma care. My current research interests are in clinical decision-making in early trauma care and pre-hospital trauma resuscitation.

Contact

email: z.perkins@qmul.ac.uk

Perkins ZB, Haines RW, Prowle JR. Trauma-associated acute kidney injury. Curr Opin Crit Care. 2019 Dec;25(6):565-572. doi: 10.1097/MCC.0000000000000655. PMID:31503027.

Vasey B, Nagendran M, Campbell B, Clifton DA, Collins GS, Denaxas S, Denniston AK, Faes L, Geerts B, Ibrahim M, Liu X, Mateen BA, Mathur P, McCradden MD, Morgan L, Ordish J, Rogers C, Saria S, Ting DSW, Watkinson P, Weber W, Wheatstone P, McCulloch P; DECIDE-AI expert group. Reporting guideline for the early-stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI. Nat Med. 2022 May;28(5):924-933. doi: 10.1038/s41591-022-01772-9. Epub 2022 May 18. Erratum in: Nat Med. 2022 Oct;28(10):2218. PMID: 35585198.

Perkins ZB, Captur G, Bird R, Gleeson L, Singer B, O'Brien B. Trauma induced acute kidney injury. PLoS One. 2019 Jan 25;14(1):e0211001. doi: 10.1371/journal.pone.0211001. PMID: 30682106; PMCID: PMC6347290.

Perkins ZB, De'Ath HD, Sharp G, Tai NR. Factors affecting outcome after traumatic limb amputation. Br J Surg. 2012 Jan;99 Suppl 1:75-86. doi: 10.1002/bjs.7766. PMID: 22441859.

Ter Avest E, Carenzo L, Lendrum RA, Christian MD, Lyon RM, Coniglio C, Rehn M, Lockey DJ, Perkins ZB. Advanced interventions in the pre-hospital resuscitation of patients with non-compressible haemorrhage after penetrating injuries. Crit Care. 2022 Jun 20;26(1):184. doi: 10.1186/s13054-022-04052-7. PMID: 35725641; PMCID: PMC9210796.

Tyler JA, Perkins Z, De'Ath HD. Intraosseous access in the resuscitation of trauma patients: a literature review. Eur J Trauma Emerg Surg. 2021 Feb;47(1):47-55. doi: 10.1007/s00068-020-01327-y. Epub 2020 Feb 20. PMID: 32078703.

Perkins ZB, Lendrum RA, Brohi K. Resuscitative endovascular balloon occlusion of the aorta: promise, practice, and progress? Curr Opin Crit Care. 2016 Dec;22(6):563-571. doi: 10.1097/MCC.0000000000000367. PMID: 27805960.

Glasgow S, Davenport R, Perkins Z, Tai N, Brohi K. A comprehensive review of blood product use in civilian mass casualty events. J Trauma Acute Care Surg. 2013 Sep;75(3):468-74. doi: 10.1097/TA.0b013e318298efb9. PMID: 23928738.

Vasey B, Nagendran M, Campbell B, Clifton DA, Collins GS, Denaxas S, Denniston AK, Faes L, Geerts B, Ibrahim M, Liu X, Mateen BA, Mathur P, McCradden MD, Morgan L, Ordish J, Rogers C, Saria S, Ting DSW, Watkinson P, Weber W, Wheatstone P, McCulloch P; DECIDE-AI expert group. Reporting guideline for the early stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI. BMJ. 2022 May 18;377:e070904. doi: 10.1136/bmj-2022-070904. PMID: 35584845; PMCID: PMC9116198.

Perkins ZB, Yet B, Glasgow S, Cole E, Marsh W, Brohi K, Rasmussen TE, Tai NR. Meta-analysis of prognostic factors for amputation following surgical repair of lower extremity vascular trauma. Br J Surg. 2015 Apr;102(5):436-50. doi: 10.1002/bjs.9689. Epub 2015 Feb 23. PMID: 25706113.

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